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Study finds racial segregation in nursing homes - Campus News
2007-09-27 14:15:00
A study co-authored by Professor of Community Health Vincent Mor found evidence of widespread racial segregation among U.S. nursing homes and a correlation between segregation and disparities in quality of care, particularly for blacks.Published in the latest issue of Health Affairs, the study found segregation was most acute in Midwest nursing home facilities and generally reflected patterns of residential segregation. Mor, chair of the community health department, served as the study's principal investigator."This study is one of the first to draw from inter-facility databases of resident information to address questions of disparity of care between nursing homes in a given metropolitan area," Mor said. "Before 1999, when these data were computerized, it was difficult to study questions relating to quality of care beyond an intra-facility level."Read more......Study finds racial segregation in nursing homes - Campus News : "Study finds racial segregation in nursing homes"
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Absolute venous thrombosis risk moderately increased after air travel
2007-09-26 17:34:00
By Liam Davenport26 September 2007PLoS Med 2007; 4: e290MedWire News: The risk for symptomatic venous thrombosis is generally increased after air travel, although only modestly, with further rises in risk seen with increasing exposure to air travel and in high-risk groups, study findings suggest.Previous studies have indicated that, after air travel, the risk for venous thrombosis is increased between two- and four-fold. However, Suzanne Cannegieter, from Leiden University Medical Center, and colleagues point out that the absolute risk for venous thrombosis after air travel is unknown.The team therefore studied 8755 employees from large international companies and organizations between 2000 and 2005, correlating travel records provided by the employers with the occurrence of symptomatic venous thrombosis. The researchers considered a flight of at least 4 hours long haul, and that exposure continues for a postflight period of 8 weeks.Click here to see the rest of this article in MedW...
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Vitamin K supplement improves anticoagulation stability
2007-09-26 17:27:00
By Liam Davenport25 September 2007J Thromb Haemost 2007; 5: 2043-2048MedWire News: Taking a vitamin K dietary supplement improves the stability of oral anticoagulation therapy with vitamin K antagonists, which could reduce bleeding and thrombotic events, report Dutch scientists.One of the disadvantages of oral anticoagulant treatment with vitamin K antagonists is unstable anticoagulant control, with the intensity of anticoagulation within the target range just 60% of the time. One of the reasons for this is a fluctuating intake of vitamin K.Click here to see the rest of this article in MedWire News Reprinted with kind permission from MedWire Newspermalink TechnoratiPhilippine Nursing http://Philippinenursing.blogspot.com
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Chlorination in swimming pools raises childhood asthma risk
2007-09-24 13:54:00
By Sara Freeman24 September 2007European Respiratory Society Annual Congress 2007; Stockholm Sweden: 15-19 SeptemberMedWire News: Children who regularly swim in chlorinated swimming pools, both indoor and outdoor, are at higher risk for developing asthma than children who do not, according to two studies presented this week at the European Respiratory Society annual congress in Stockholm, Sweden.An Italian team described how young competitive swimmers, who regularly trained in an indoor pool, had a much higher rate of allergic sensitization than would be expected. Some of these children also had bronchial hyperreactivity (BHR) to methacholine.Meanwhile, Belgian researchers presented data that showed how regular attendance at an open-air pool can increase immunoglobulin (Ig)E levels and asthma risk in children.The premise behind both studies is that toxic chlorination products just above the surface of the water can damage the airways of children if breathed regularly enough."The lev...
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Cancer May Be Prevented By Controlling Organ Size
2007-09-24 05:42:00
Scientists at Johns Hopkins recently discovered that a chemical chain reaction that controls organ size in animals ranging from insects to humans could mean the difference between normal growth and cancer. The study, published in the Sept. 21 issue of Cell, describes how organs can grow uncontrollably huge and become cancerous when this chain reaction is perturbed."This chain reaction, a domino-like chain of events we call the Hippo pathway, adds a single chemical group on a protein nicknamed Yap," says lead author Duojia Pan, Ph.D., associate professor of molecular biology and genetics. "The good news is that maybe all organ growth can be reduced to this one chemical event on the Yap protein -- but the better news is that we potentially have a new target for cancer therapy."Pan and colleagues previously had discovered in fruit flies that too much Yap supercharges growth-inducing genes and causes organs to overgrow.In the new study designed to see if the same effect occurred in mamm...
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--Nursing News Abroad--- Your Health is Being Jeopardized by Nursing Shorta
2007-09-20 18:42:00
Your health, and the health of your audience, is being jeopardized by nursing shortages. RealityRN.com, launching October 10, is the first and only website whose goal is to combat the shortage and decrease patient mortality rates in hospitals by focusing on new nurses and keeping new nurses in the profession. Nurses are available now for interviews. Chicago, IL (PRWEB) September 20, 2007 -- Your health is being jeopardized by nursing shortages. RealityRN.com, launching October 10, is the first and only website whose goal is to combat the shortage and decrease patient mortality rates in hospitals by focusing on new nurses and helping to keep them in the profession. The federal government is projecting a shortage of one million nurses and 24,000 doctors in the U.S. by 2020. According to a 2006 report by the Metropolitan Chicago Heal th care Council, Illinois will face a shortage of 21,000 registered nurses by 2010. Two-thirds of these vacancie...
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--Nursing News Abroad---Union: Nursing shortage affecting patient care
2007-09-20 18:38:00
Posted Thu Sep 20, 2007 9:50am AESTUpdated Thu Sep 20, 2007 10:02am AESTThe Australian Nursing Federation is warning the quality of patient care in Western Australia's public hospitals is in danger of declining due to a massive shortage of nurses The Federation's State Secretary Mark Olson says new figures show the public health system is short by 1,070 nurses. Mr Olson says Sir Charles Gairdner Hospital is one of the worst affected, down 110 nurses. He says the care of premature babies in King Edward Memorial Hospital and Princess Margaret Hospital is also suffering significantly due to the shortage. "We face the very real risk that in an area like the special care nursery we may have to transfer patients to Adelaide because we simply won't be able to provide the service in Western Australia and what a shocking situation that would be," he said. "We continue to hear stories from the floor of people who are under enormous stress, staff are working very long hours, sometimes worki...
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Diagnostic Blood Test Could Screen For Lung Cancer, Even At Earliest Stage
2007-09-20 14:27:00
Biopharmaceutical researchers have found a protein in blood they say is linked to all stages of lung cancer but which rarely shows up in the blood of people without the disease. Test ing for this protein might help physicians decide whether smokers or others at high risk for lung cancer should be referred for lung imaging, say investigators, who presented their findings in Atlanta, Georgia at the American Association for Cancer Research's second International Conference on Molecular Diagnostics in Cancer Therapeutic Development.A diagnostic blood test to screen high-risk individuals for lung cancer could be both practical to use and cost-effective, say investigators from Panacea Pharmaceuticals, Inc., of Gaithersburg, Md."A positive test for this protein marker, followed by CT scanning, may help identify individuals with lung cancer at a stage in which treatment is more effective, possibly even curative," said research scientist Mark Semenuk, who is presenting results of a study tes...
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Misconceptions About Alzheimer's Varies Among Races
2007-09-19 09:57:00
Alzheimer's disease is still a mystery to people of different races and a large percentage of people across the board are unaware that treatments are available to reduce symptoms.This is one of the surprising findings in a national survey, "Public opinion about Alzheimer's disease among Blacks, Hispanics, and Whites," which was analyzed by researchers at the University of Michigan School of Public Health. Understanding racial and ethnic influences on knowledge and beliefs about Alzheimer's is critical to communicating risk reduction strategies, symptom recognition, diagnosis and illness management, the paper said.There were more similarities in patterns of response among the racial groups than expected, said Cathleen Connell, professor in the U-M School of Public Health and director of the Education and Information Transfer Core of the Michigan Alzheimer's Disease Research Center. One half of the sample reported that nothing can be done to maintain cognitive functioning and redu...
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Vitamin E fights VTE risk in women
2007-09-19 09:50:00
By Lynda Williams18 September 2007Circulation 2007; 116: Advance online publicationMedWire News: Vitamin E supplements significantly reduce the risk of venous thromboembolism (VTE) by up to almost 50%, results from the Women 's Health Study (WHS) demonstrate."Given its lack of efficacy for prevention of cardiovascular disease and cancer, vitamin E may be most appropriate for people at high risk of VTE," Robert Glynn (Brigham and Women's Hospital, Boston, Massachusetts, USA) and team say.As vitamin E is thought to inhibit vitamin K and vitamin K-dependent clotting factors, the researchers examined WHS findings to determine whether the vitamin alters the risk for VTE.In all, 39,876 women aged 45 years and older were randomly assigned to take vitamin E 600 IU on alternate days or placebo. Blood samples for 26,779 women were tested for known prothrombotic mutations.Over a median of 10.2 years of follow-up, 482 women developed VTE. A total of 213 episodes occurred in those given vitamin...
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--Nursing News Abroad---Nurse training proposal represents a backwards ste
2007-09-17 09:34:00
I am writing in response to the proposed hospital-based schools of nursing ("Training plan puts patients at risk: nurses", September 15, p2). I add two points to the debate. First, the programs raise an issue of equity. University of Canberra nursing students pay to study and learn by working two to three days per week in community health, residential aged care, mental health, as well as hospital services. The work is unpaid, with many students doing paid work to support themselves and their families. Part-time study is increasing, effectively delaying graduation and entry into the workforce. Students in the proposed 18-month enrolled nurse programs will be paid a weekly salary hardly a fair use of limited federal resources. Second, the Government's press release (September 14) suggests that administrators and doctors will have greater input into the educational program. This self-serving approach, where the same people who seek to control nursing work and nurses design the pro...
More About: News , Proposal , Nurse , Nursing

Cholesterol Byproduct Blocks Heart Health Benefits Of Estrogen
2007-09-17 09:31:00
New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease. The results of the study, available online and in the October issue of the journal Nature Medicine, also may explain why hormone replacement therapy fails to protect some postmenopausal women from heart disease, said Dr. David Mangelsdorf, chairman of pharmacology and senior author of the paper.The researchers found that in rodents, a molecule called 27-hydroxycholesterol, or 27HC, binds to the same receptors in the blood vessels of the heart to which estrogen binds.The normal result of this estrogen binding is that blood vessel walls remain elastic and dilated, and damage to the vasculature is repaired, among other heart protective effects. Other research has shown that postmenopausal women who no...
More About: Health , Heart , Benefits , Cholesterol , Blocks

Linchpin Gene May Be Useful Target For Breast Cancer Therapies
2007-09-16 12:47:00
University of Iowa researchers have discovered a gene that plays a linchpin role in the ability of breast cancer cells to respond to estrogen. The finding may lead to improved therapies for hormone responsive breast cancers and may explain differences in the effectiveness of current treatments.Estrogen causes hormone responsive breast cancer cells to grow and divide by interacting with estrogen receptors made by cancer cells. Interfering with estrogen signaling is the basis of two common breast cancer therapies -- tamoxifen, which blocks estrogen's interaction with a primary estrogen receptor called ER alpha, and aromatase inhibitors that reduce the amount of estrogen the body makes and therefore affect any pathway that uses estrogen.The study, led by Ronald Weigel, M.D., Ph.D., professor and head of surgery at the University of Iowa Roy J. and Lucille A. Carver College of Medicine, reveals a central role for transcription factor AP2C (TFAP2C) in controlling multiple pathways of es...
More About: Cancer , Breast Cancer , Breast , Target , Gene

Heart Medications: The More You Skip, The More You Risk
2007-09-15 21:05:00
Although it might take some effort to find out why some patients skip taking their medicine, a new study finds that heart patients who most frequently miss a dose are more than twice as likely to suffer heart attack, stroke and death.The findings are important because they pinpoint the size of the problem, said study co-author Mary Whooley, M.D., associate professor of medicine at the University of California at San Francisco. Just over 8 percent of the 1,015 patients surveyed said they fail to take their medicine at least 25 percent of the time."The next step is to figure out how we can change people's behavior," Whooley said. "It is so hard to convince people to lose weight, exercise and take their medicines as they're supposed to. If we could figure out ways to motivate people to change, that would have tremendous public health consequences."Whooley and colleagues asked coronary heart patients taking part in a national study whether they took their medications over the past mon...
More About: Heart , Risk , Medications , Cardiology

Managing Chronic Pain
2007-09-15 21:01:00
Approximately 30% of Canadians suffer daily from chronic pain. Patients may be affected differently depending on the intensity, but all chronic pain is debilitating and difficult to treat. A study carried out by Louise Lamb, a clinician nurse at the Pain Centre of the Montreal University Health Centre (MUHC), and Dr. Yoram Shir, the Director of the Centre, shows that methadone in combination with innovative and high-quality case management can provide relief for many patients. The study results are published in the September issue of Pain Management Nursing.Methadone is most often associated with drug addiction treatment, yet this opioid is regularly used in hospital settings to relieve acute pain from cancer or arthritis or following an accident.Because the body metabolizes methadone slowly, intense monitoring is required to avoid toxicity. "As an ambulatory centre, we needed a way to monitor patients effectively after they go home with their prescriptions," explained Ms. Lamb. The...

15 Month Old Kids Should Have Cholesterol Test
2007-09-14 15:31:00
A person's first cholesterol test should take place when he/she is 15 months old, according to an article in the British Medical Journal (BMJ). The authors explain that familial hypercholesterolemia, high LDL cholesterol levels that runs in families, carries a significant risk of death from coronary heart disease.Approximately 2 out of every 1,000 people have familial hypercholesterolemia. There are treatments available today which can decrease the risk of death from coronary heart disease for such people.Scientists at Barts and the London Queen Mary's School of Medicine and Dentistry, UK, examined 13 prior studies which focused on total and LDL cholesterol in people with and without familial hypercholesterolemia, involving 1,907 cases and 16,221 controls. They wanted to find out how effective screening might be, and if so, at what age.For screening to be most effective, the authors wrote, it needs to be done when a child is aged between 1 and 9 years. At this age screening detect...
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The Psychology Of Our Desire For Chocolate
2007-09-14 15:29:00
Chocolate is the most widely and frequently craved food. People readily admit to being 'addicted to chocolate' or willingly label themselves as 'chocoholics'. A popular explanation for this is that chocolate contains mood-enhancing (psychoactive) ingredients that give it special appeal.Evidence and logic, however, find little support for this. Substances present in chocolate which have been highlighted as potentially pharmacologically significant include serotonin, tryptophan, phenylethylamine, tyramine and cannabinoids. However, many of these compounds exist in higher concentrations in other foods with less appeal than chocolate.Professor Peter Rogers, from the University of Bristol, UK, explains: "A more compelling explanation lies in our ambivalent attitudes towards chocolate -- it is highly desired but should be eaten with restraint (nice but naughty). Our unfulfilled desire to eat chocolate, resulting from restraint, is thus experienced as craving, which in turn is attribut...
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State needs to cope with a growing doctor shortage
2007-09-13 17:41:00
PHYSICIANS are in short supply in rural areas across the country, and the shortage is felt in Hawaii's neighbor islands. Combined with a nursing shortage that is projected to worsen, Hawaii could face a health care crisis that will require action to produce and retain more medical workers in the islands. Hawaii has about three physicians for every thousand residents, ranking it 11th among states in doctors per capita. Still, the state has a shortage of specialists such as orthopedic surgeons, anesthesiologists, gynecologists and general family doctors, who are especially scarce on neighbor islands. John Bellatti, a Kona orthopedic surgeon, predicted to the Star-Bulletin's Nina Wu that "the all-out shutdown of private medical doctors is on the horizon. There will still be a very few maintaining their existing practices and large parts of the population will have no doctor." More than 35 million Americans live in areas that are underserved in health care, and the American Medical As...
More About: State , Growing , Doctor , Grow , Cope

The Adult Brain Retains 'Fetal' Neurons
2007-09-13 17:39:00
Subplate neurons -- once thought to die after directing the wiring of the cerebral cortex or gray matter-- remain in the white matter of the adult brain in small numbers and maintain activity, communicating with other neurons in the brain said researchers from Baylor College of Medicine and the University of Alabama at Birmingham in a report that appears in the Journal of Neuroscience.The finding -- that approximately 10 percent of the cells survive and have functional connections -- opens the door to new ways of thinking about fixing injured brains, said Dr. Michael Friedlander, chair of the department of neuroscience at BCM, and senior author of the paper. "Since those cells are critical elements that guided the wiring of the brain's cerebral cortex in the first place, maybe we could tap into that ability later on."However, he emphasized that this just a hypothesis and has yet to be proven. Friedlander credits an M.D./Ph.D. student of his, Dr. Juan Torres-Reveron, with coming up ...
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Scientists Find Clues To Crack "Neural Code" of The Brain
2007-09-13 13:33:00
Decoding the complex electrical signals that brain cells use to "talk" to each other is a new and important frontier in neuroscience, one that could revolutionize the diagnosis and treatment of neurological and psychiatric disease.Now, a multicenter team, led by a researcher at Weill Cornell Medical College in New York City, says they have uncovered a vital clue to help decode that neural language.The groundbreaking work is published in Nature."We discovered that the specific timing of these electrical pulses is crucial to interpreting how the neural code works as the brain represents what it sees in the natural environment. Understanding the 'time scales' that matter to the brain gives us insight into which units of the neural code we need to focus on if we ever hope to decode it," explains lead author Dr. Daniel A. Butts, who is an Institute Fellow and instructor of computational neuroscience at the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational B...
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Genetic Risk Factor For Rheumatoid Arthritis, Lupus, Identified By Study
2007-09-13 13:26:00
A genetic variation has been identified that increases the risk of two chronic, autoimmune inflammatory diseases: rheumatoid arthritis (RA) and systemic lupus erythematosus (lupus). These research findings result from a long-time collaboration between the Intramural Research Program (IRP) of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other organizations. NIAMS is part of the National Institutes of Health.These results appear in the New England Journal of Medicine."Although both diseases are believed to have a strong genetic component, identifying the relevant genes has been extremely difficult," says study coauthor Elaine Remmers, Ph.D., of the Genetics and Genomics Branch of the Intramural Research Program at the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Dr. Remmers and her colleagues tested variants within 13 candidate genes located in a region of chromosome 2, which they had previously linked with RA, for ass...
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College Network introduces surefire way to pass NCLEX
2007-09-11 15:01:00
By Krista Angela Montealegre , Special to The Manila Times WITH the Philippines now one of its accredited testing sites, the professional review organization Coll ege Network is bringing to the Filipino nurses a guaranteed way to pass the National College Licensure Examination (NCLEX). This is the equivalent of a comprehensive board examination in the United States. Majority of Filipino nurses go to the United States to practice their profession. This is the main reason why the College Network decided to bring its NCLEX-Registered Nurse (RN) program in the Philippines. With a similar lifestyle between Filipinos and the Americans, their English-proficiency and their hospitability, Filipinos are the most-sought-after nurses in the US. ...
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Pre-Eclampsia Linked With Low Vitamin D During Pregnancy
2007-09-11 12:58:00
Vitamin D deficiency early in pregnancy is associated with a five-fold increased risk of preeclampsia, according to a study from the University of Pittsburgh Schools of the Health Sciences reported in the Journal of Clinical Endocrinology and Metabolism.A serious complication of pregnancy marked by soaring blood pressure and swelling of the hands and feet, preeclampsia is the leading cause of premature delivery and maternal and fetal illness and death worldwide, conservatively projected to contribute to 76,000 deaths each year. Preeclampsia, also known as toxemia, affects up to 7 percent of first pregnancies, and health care costs associated with preeclampsia are estimated at $7 billion a year in the United States alone, according to the Preeclampsia Foundation."Our results showed that maternal vitamin D deficiency early in pregnancy is a strong, independent risk factor for preeclampsia," said Lisa M. Bodnar, Ph.D., M.P.H., R.D., assistant professor of epidemiology at the University...
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MRI shows abnormal cognitive activity in patients with psychosis
2007-09-11 12:55:00
By Andrew Czyzewski11 September 2007Arch Gen Psychiatry 2007; 64: 999-1014MedWire News: Patients with psychosis show reduced temporal brain activity when performing certain memory-encoding tasks, study findings indicate.Among 26 patients with first-episode psychosis, the hippocampus showed normal modulation of activation during successful memory encoding, but abnormal activity during encoding of arbitrary pairs, compared with 20 healthy controls.Amélie Achim (Brain Imaging Group, Douglas Hospital Research Université de Montréal, Quebec, Canada) and colleagues speculate that people who struggle to discriminate between arbitrary and related pieces of information may be prone to psychotic disorders.The researchers note, however, that "the normal modulation of hippocampal activation observed during successful memory encoding in first-episode psychosis argues against a general inability to recruit this region."Memory is greatly affected in schizophrenia. Behavioral observations suggest t...
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Studying The Capacity For Change in The Adult Brain
2007-09-10 16:12:00
It is well established that a child's brain has a remarkable capacity for change, but controversy continues about the extent to which such plasticity exists in the adult human primary sensory cortex. Now, neuroscientists from MIT and Johns Hopkins University have used converging evidence from brain imaging and behavioral studies to show that the adult visual cortex does indeed reorganize-and that the change affects visual perception. The study appears online in an advance publication of the Journal of Neuroscience.The authors believe that as scientists find ways to use this adaptive ability, the work could have relevance to topics ranging from learning to designing interventions for improving recovery following stroke, brain injury, or visual disorders.Animal studies conducted two decades ago and using single cell recording of neurons found that the adult animal brain can change, but shed little information about the adult human brain. In 2005, a functional magnetic resonance imagi...
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Depression 'causes greatest health reduction in chronic diseases'
2007-09-10 16:09:00
By Liam Davenport10 September 2007Lancet 2007; 370: 851-858MedWire News: Depression is more damaging to health than other chronic diseases such as angina, arthritis, asthma, and diabetes, reports an international team of researchers.They also report that comorbid depression is more damaging to health than depression alone, and say their findings show that improving the treatment of depression should be a public health priority.Little previous research has sought to determine how overall health status is impacted by depression, either alone or as a comorbity, say the researchers.The International Classification of Diseases -10 criteria were used to estimate the prevalence of depression. Algorithms developed from the Diagnostic Item Probability Study allowed researchers to calculate the prevalences of angina, arthritis, asthma, and diabetes. Factor analysis was used to construct average health scores, which were compared across different disease states and demographic variables.The 1-y...
More About: Health , Seas , Reduction

How Insulin Secreting Cells Maintain Their Glucose Sensitivity
2007-09-09 16:17:00
Scientists at the leading Swedish medical university Karolinska Institutet have resolved the mystery of how insulin-secreting cells maintain an appropriate number of ATP sensing ion channel proteins on their surface. This mechanism, which is described in the latest issue of Cell Metabolism, explains how the human body can keep the blood glucose concentration within the normal range and thereby avoid the development of diabetes.Blood sugar absorbed from food is timed to enter muscles as energy supply as well as the liver and fat tissue for energy storage. Otherwise, diabetes occurs. Such glucose transport is precisely controlled by insulin, the body's only hormone capable of lowering blood sugar. This hormone is released from insulin-secreting cells in the pancreas.Click here to see the rest of this article in Medical News Todaypermalink TechnoratiPhilippine Nursing http://Philippinenursing.blogspot.com

----Nursing News Abroad----Hundreds Of RNs From Across U.S. And World To Jo
2007-09-08 11:29:00
The California Nurses Association/National Nurses Organizing Committee will convene its national convention in Sacramento Monday, greeting hundreds of registered nurses from around the U.S. and the world - and pressing the campaign for genuine, guaranteed healthcare reform in California and Washington. The conference is at the Sacramento Convention Center.Highlighting the proceedings, convention delegates joined by community supporters will march to the Capitol Tuesday for a rally to press the case with California legislators and Gov. Arnold Schwarzenegger for real reform, not just cosmetic changes that reinforce the insurance-based system that created the current crisis.Click here to see the rest of this article in Medical News Todaypermalink TechnoratiPhilippine Nursing http://Philippinenursing.blogspot.com
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ECG does not rule out LV hypertrophy
2007-09-08 11:26:00
By Caroline Price07 September 2007Br Med J 2007; Advance online publicationMedWire News: Electrocardiographic criteria should not be used to rule out left ventricular (LV) hypertrophy in patients with hypertension, say clinicians in an advance online publication by the British Medical Journal.Matthias Egger (Universities of Bern, Switzerland, and Bristol, UK) and colleagues conclude this after conducting a systematic review of studies testing the accuracy of six different electrocardiographic indexes.Accurate and early diagnosis of LV hypertrophy is an important component of the care of hypertension patients, in whom it leads to a five- to 10-fold increase in cardiovascular risk, explain the researchers, but the appropriate diagnostic work-up of suspected LV hypertrophy remains unclear.Egger and co-workers set out to clarify the accuracy of commonly used electrocardiographic indexes, focusing on their ability to rule out LV hypertrophy in patients with arterial hypertension."As the ...
More About: Cardiology , Rule , Hyper , Pert

Antibody boosts anti-lung cancer RT
2007-09-08 04:34:00
By Liam Davenport07 September 2007Clin Cancer Res 2007; 13: 5211-5218MedWire News: The anti-tumor effects of radiation therapy (RT) could be enhanced using the antiphosphatidylserine antibody 2aG4 to target phosphatidylserine on the luminal surface of tumor blood vessels, thereby making the vessels more vulnerable to cell-mediated cytotoxicity, indicate preliminary study results in mice.The researchers conducted the study to find out whether RT could increase the exposure of phosphatidylserine on tumor vasculature and so enhance the effects of 2aG4.Philip Thorpe, from the University of Texas Southwestern Medical Center at Dallas, USA, and colleagues studied the effects of RT plus 2aG4 on mice with radiation-resistant A549 human lung tumors. One group of mice was treated with RT plus 2aG4, while another received 2aG4 alone. A third group of untreated mice acted as controls.Immunofluorescence staining was used to determine radiation-induced phosphatidylserine exposure on endothelial c...
More About: Lung Cancer , Anti