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Breast Cancer And Type Of Hormonal Drug
2007-02-01 17:24:01
Aromatase inhibitors, a type of hormone treatment used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when in comparison to other hormone therapys, as per a new systematic review of studies. In addition, aromatase inhibitors -- drugs known as Arimidex, Aromasin and Femara -- are less likely to cause blood clots and vaginal bleeding than other hormone therapys, said review co-author Judith Bliss of the Institute of Cancer Research in London........
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Estrogen Interferes With Breast Cancer surveillance
2007-01-26 05:19:32
Estrogen is known to enhance the growth and migration of breast cancer cells. Now scientists at the University of Illinois at Urbana-Champaign have observed that estrogen also can shield breast cancer cells from immune cells. As per a research findings published online this week in Oncogene, the scientists report that estrogen induces the expression of an inhibitor that blocks immune cells' ability to kill tumor cells. This is the first study to identify estrogen's role in shielding breast cancer cells from the action of immune cells........
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Scientists have linked a structural protein called nestin to
2007-01-16 05:12:02
Scientists have linked a structural protein called nestin to a especially deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better therapy. In the January 15 issue of Cancer Research, scientists from Dartmouth Medical School demonstrate that nestin could represent a selective biological marker for basal epithelial breast tumors, a highly aggressive cancer with similarities to mammary stem cells, the regenerative cells thought to bethe site of breast cancer initiation........
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New Target For The Treatment Of Breast Cancer
2007-01-12 17:09:02
The active ingredient in a drug currently being tested to treat rheumatoid arthritis might also one day serve as an effective means of treating one of the deadliest forms of breast cancer. Scientists with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have demonstrated that inhibiting the activity of the protease enzyme known as TACE can deprive tumor cells of a key factor needed for their proliferation. TACE is strongly present in a form of breast cancer which responds poorly to current therapies........
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Online Prayer May Help Breast Cancer Patients
2007-01-11 05:07:08
Interesting news on breast cancer reported by Reuters and CNN. Praying online in a support group may help women with breast cancer cope with the disease more effectively, a new study shows. Dr. Bret Shaw of the University of Wisconsin-Madison and colleagues found that breast cancer patients who used a higher percentage of religion-related words in their communications with an Internet support group had lower levels of negative emotions, better functional well-being, and more confidence in their ability to deal with their illness........
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Black Women And Breast Cancer Survival
2006-12-19 10:55:02
A number of prior studies have shown that African-American women generally perform worse when it comes to breast cancer survival. This is true even after taking into consideration such factors as tumor size and socioeconomic differences, according to a new study. "I think it's due to biological factors in the actual cancer, and this means that race may be a surrogate for a more adverse molecular profile within the cancer," said Dr. Kathy Albain, the study's senior researcher and a professor of medicine at Loyola University Chicago Medical Center........
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Aromasin after tamoxifen
2006-12-19 10:55:02
San Antonio breast cancer conference brings the latest research work in the field of breast cancer. This is an annual event where breast cancer scientists all over the world come together to present the research findings. In one of the studies presented at the San Antonio breast cancer meeting it was shown that after surgery for early-stage breast cancer, women may be treated with tamoxifen for 5 years. After that point, therapy with Aroma sin significantly improves survival, as per a new study........
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Detecting Breast Cancer Metastases Early
2006-12-19 10:55:02
Results from a prospective clinical study show that the GeneSearch- Breast Lymph Node (BLN) Assay, a gene-based diagnostic test has greater sensitivity than traditional intra-operative methods of detecting the spread of breast cancer to the lymph nodes. In the study sponsored by Veridex, LLC, the GeneSearch- BLN Assay demonstrated overall sensitivity at least 10 percentage points higher than traditional intra-operative tests. The data were presented today at the 29th Annual San Antonio Breast Cancer Symposium........
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Advances In Breast Imaging
2006-12-18 22:54:02
A diagnostic device that resembles a mammography unit can detect breast tumors as tiny as one-fifth of an inch in diameter, which may make it a valuable complementary imaging technique to mammography, say scientists at Mayo Clinic, who helped develop the technology along with industry collaborators Gamma Medica and GE Healthcare........
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Use Of Mammograms In Men Is Rising
2006-12-18 22:54:02
A number of men have breast symptoms, including enlarged or painful breast tissue, but the majority do not need a mammogram, say scientists from Mayo Clinic Cancer Center. Mammograms are used to check for the presence of breast cancers, which are very rare in males. Their study, presented Saturday, Dec. 16, at the 2006 meeting of the San Antonio Breast Cancer Symposium, suggests physicians should reconsider ordering mammograms for men, who are most often diagnosed with non-malignant gynecomastia, a common condition which includes breast swelling, a tender mass or painful breast tissue........
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Breast Cancer Patients May Not Follow Hormonal Therapy
2006-12-18 22:54:02
Postmenopausal women with early-stage, hormone-sensitive breast cancer have a lower risk of disease recurrence when their treatment includes a new class of hormone therapy drugs, yet one out five women prescribed the drugs may not take them regularly, according to a study conducted by researchers at Dana-Farber Cancer Institute and AstraZeneca Pharmaceuticals. Their findings will be presented at the 29th annual San Antonio Breast Cancer Symposium on Saturday, Dec. 16 (Abstract 4044)........
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Reduce Fat Intake Say Breast Cancer Experts
2006-12-17 10:53:01
For a number of years scientists were arguing if increased fat intake would increase the risk of breast cancer. Now a team of scientists has observed that reducing the amount of dietary fat intake may actually decrease the chance of a breast cancer recurrence in women who have been treated for early-stage breast cancer. This is not just speculation, but based on solid evidence revealed by a phase III randomized, clinical trial in the latest issue of the Journal of the National Cancer Institute........
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Biomarkers To Predict Potential For Breast Cancer Spread
2006-12-16 10:52:03
Researchers are always trying to find ways to predict the behaviors of cancer cells. One area of interest is to identify proteins and other biomarkers associated with the potential of cancer spread. Over the years many biomarkers were identified and the researchers are continuing to uncover more of these. Recently researchers found that expression of two different proteins taken from primary tumor biopsies is highly associated with spread of breast cancer to nearby lymph nodes. Researcher say this protein profile could help identify at an early stage those patients whose disease is likely to metastasize........
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New Antibody Test On Mice with Breast Cancer
2006-12-13 10:51:08
Herceptin, a monoclonal antibody is well known to physicians and patients with breast cancer. It has been described as the miracle drug. Now a new monoclonal antibody developed by researchers at the University at Buffalo has been shown to extend significantly the survival of mice with human breast-cancer tumors and to inhibit the cancer's spread to the lungs in the animals by more than 50 percent........
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Breast Cancer Screening Trials For Under 50s
2006-12-13 10:51:08
A ten year trial in which women between the ages of 40 and 50 were invited for annual breast screening did not show a significant reduction in breast cancer mortality. The report by scientists at The Institute of Cancer Research is published recently in the Lancet. The trial was funded by Cancer Research UK, the Medical Research Council and the Department of Health. It involved around 160,000 women, of whom a third received annual screening invitations and two-thirds usual medical care........
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Big Magnet Ready To Face The Big Questions
2006-12-02 16:42:17
The largest superconducting magnet ever built has successfully been powered up to its operating conditions at the first attempt. Called the Barrel Toroid because of its shape, this magnet is a vital part of ATLAS, one of the major particle detectors being prepared to take data at CERN's Large Hadron Collider (LHC), the new particle accelerator scheduled to turn on in November 2007. ATLAS will help scientists probe the big questions of the Universe - what happened in the moments after the Big Bang? Why does the material in the Universe behave the way it does? Why is the Universe we can see made of matter rather than anti-matter?.......
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Cancer In Women With Rare Breast Condition
2006-12-02 16:42:17
Women whose mammograms reveal a suspicious lesion need a needle biopsy to confirm or rule out cancer. But if that biopsy reveals only abnormal - not cancerous - cells, is a more extensive evaluation necessary? Yes, suggests a new study by doctors at Washington University School of Medicine in St. Louis. They looked at the medical records of women whose initial core-needle breast biopsies found rare, yet non-cancerous breast conditions: atypical lobular hyperplasia (ALH) or lobular carcinoma-in-situ (LCIS). These lesions are known to increase a woman's risk of breast cancer, but what the researchers found was surprising........
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Face The Sun
2006-12-02 16:42:17
Three years ago I watched helplessly as my wife lost a close childhood friend to breast cancer after she was originally misdiagnosed, and told she was too young to get breast cancer. Diane courageously battled the illness, enduring both mainstream and alternative therapys, all the while reminding those around her of the precious nature of each day of life. In an effort to raise awareness about breast cancer, and to pay tribute to Diane, I spent the years since her passing writing a screen play which follows a young woman and family dealing with breast cancer. Through the recently formed, Sunflower Pictures, that script is now in what is referred to as the "pre-production phase"........
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Negative Brca Test Doesn't Guarantee Safety
2006-12-02 16:42:17
In women with a strong family history of breast cancer a negative BRCA test does not necessarily guarantee safety from breast cancer. These women are still at increased risk of developing the disease as per findings from the latest research. These women should start breast cancer screening at earlier age from 35 to 40 years........
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Breast Cancer Therapy In Which Order?
2006-12-02 16:42:17
For women who have had surgery for early breast cancer, it may not matter whether they receive follow-up chemotherapy before, after or during radiation treatment, as per a new review of studies. A woman's chances of survival or seeing the cancer return are similar in all three cases, if radiation treatment and chemotherapy begin within seven months after surgery, the review concludes........
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Regular Exercise Keeps Breast-cancer Away
2006-12-02 16:42:17
Postmenopausal women who want to significantly decrease their breast-cancer risk would be wise to exercise regularly and keep their weight within a normal range for their height, as per new findings from the Women's Health Initiative would be reported in the journal Obesity. The multicenter team of researchers, led by Anne McTiernan, M.D., Ph.D., of Fred Hutchinson Cancer Research Center, observed that women who had the lowest body-mass index, or BMI, and the highest physical-activity levels had the lowest levels of circulating estrogens, sex hormones that can fuel breast-cancer growth........
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Ethnic Variations In Hormone Levels And Breast Cancer
2006-12-02 16:42:17
Researchers have known that a woman's natural hormone levels can affect her risk of developing breast cancer. A new study from the University of Southern California (USC) has found that the natural levels of estrogens in post-menopausal women varies by ethnicity and race, and may explain the differences in the groups' breast cancer rates. The study appears in the recent issue of Cancer Epidemiology, Biomarkers and Prevention........
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Geometry Of Breast Cell Invasion
2006-12-02 16:42:17
Apropos of National Breast Cancer Awareness month, researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development. The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics but also by geometry. Though created specifically for the study of breast tissue, this model should also be applicable to the study of tissue development in other organs as well........
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Psychological Needs Of New Breast Cancer Patients
2006-11-14 01:27:01
Almost half of newly diagnosed patients with breast cancer are found to have clinically significant emotional distress or symptoms of psychiatric disorders before therapy is begun, as per a new study reported in the recent issue of CANCER, a peer-evaluated journal of the American Cancer Society. The study reveals that while virtually all of the women admitted to,experiencing some level of emotional distress, 47 percent met clinically significant screening criteria for emotional distress or a psychiatric disorder, including major depression and post-traumatic stress disorder (PTSD)........
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Breast Cancer Chemo Drugs And Cognitive Dysfunction
2006-11-10 13:03:02
Chemotherapy drugs might cause cognitive dysfunction on the recipients as per new research findings. A new study on mice has confirmed what many cancer patients receiving treatment have often complained about a decline in their memory and other cognitive functions, often characterized as "chemobrain"........
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linking ethnic identity to breast cancer genes
2006-11-10 13:03:02
Genetic research over the past decade has linked Ashkenazi Jewish ethnicity to an increased risk for hereditary breast cancer, so much so that certain gene mutations have become known as "Jewish ancestral mutations." But a new study released in the recent issue of The American Journal of Public Health challenges this approach, warning that disparities in access to care and other unintended consequences can, and have, resulted........
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Women With Mental Disorders And Mammograms
2006-11-10 13:03:02
Women with mental disorders are less likely to have screening mammograms than women without mental illness, although. the nature of the mental illness does play a role, as per a large study published by Indiana University School of Medicine and Richard Roudebush VA Health Services Center for Excellence scientists in the recent issue of Journal of General Internal Medicine. Previous to this study, little was known about whether the type or severity of mental illness influences receipt of preventive services such as mammograms........
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Older Breast Cancer Patients May Be Under-treated
2006-11-10 13:03:02
Elderly patients with breast cancer who received care in a community hospital setting may have been under-diagnosed, under-staged and under-treated, according to a report in the recent issue of Archives of Surgery, one of the JAMA/Archives journals. The number of older breast cancer patients has increased along with overall elderly population, according to background information in the article. About half of breast cancer patients are older than 65 years and 35 percent are older than 70; 77 percent of breast cancer deaths occur in women older than 55. Choosing the appropriate treatment for older patients is a challenge, because many have other serious illnesses in addition to their cancer that may threaten their health and shorten their lives. Questions remain about the best screening protocols for elderly women, as well. Some current guidelines suggest that women stop having mammograms at age 70, while others provide no upper limit........
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Vitamin D Can Fight Breast Cancer
2006-11-10 13:03:02
Vitamin D may help curb breast cancer progression, according to a study published recently in the Journal of Clinical Pathology. The authors, from Imperial College London, measured the levels of vitamin D in the blood serum of 279 women with invasive breast cancer. The disease was in its early stages in 204 of the women, and advanced in the remaining 75........
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Breast Reconstruction Not Very Safe For Obese
2006-11-10 13:03:02
Significantly obese women may wish to consider delaying breast reconstruction following mastectomy until they achieve a healthier body weight. According to findings presented today at the American Society of Plastic Surgeons (ASPS) Plastic Surgery 2006 conference in San Francisco, women who are significantly obese are at higher risk for complications and have a lower satisfaction rate than do normal and overweight patients........
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