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New gene linked to breast cancer
2007-10-08 16:56:00 Scientists in a multicenter international study have identified a new gene that, if mutated, may increase a womans risk of breast cancer by more than a third. Further, the scientists observed that the gene, HMMR, interacts with the well-known breast cancer gene BRCA1. Alternations in either gene cause genetic instability and interfere with cell division, which could be a path to breast cancer developing. This leads scientists to not just a single gene, but a pathway that may be a potential target for treating or detecting breast cancer........ More About: Cancer , Breast Cancer , Breast , Gene , Brea
Dietary calcium to prevent the spread of breast cancer
2007-10-03 06:26:00 A strong skeleton is less likely to be penetrated by metastasizing cancer cells, so a fortified glass of milk might be the way to block cancers spread, as per scientists at the ANZAC Research Institute in Concord, Australia. Using a mouse model of breast cancer metastasis, the scientists observed that a calcium deficiency may increase the tendency of advanced breast cancer to target bone. Dietary calcium, they reason, might help prevent the spread of breast cancer to bone and serve as an adjuvant therapy during treatment........ More About: Cancer , Breast Cancer , Breast , Spread
New methods of beating breast cancer
2007-10-02 06:24:00 University of Manchester scientists will reveal new ways of controlling and treating breast cancer at the National Cancer Research Institute conference in Birmingham today (Monday 1 October 2007). Dr Robert Clarke and his team at the University's Cancer Studies research group have been investigating human breast cancers for the presence of stem cells - cells that generate new tumours and can cause the cancer to recur - in a series of studies funded by the charity Brea st Cancer Campaign........ More About: Methods
Breast cancer survivors optimistic
2007-09-26 05:45:00 The majority of breast cancer survivors consider themselves stronger after having the disease, as per new survey results released recently. However, the data also suggest womens knowledge about actions they can take to lessen the likelihood of recurrence is surprisingly low. The survey, which was commissioned by AstraZeneca and conducted by Harris Interactive, consisted of interviews with 543 women in the United States who had been diagnosed with breast cancer. The vast majority (92 percent) of these women reported a positive change in their lifestyles since being diagnosed with the disease and nearly two-thirds (63 percent) said they are hopeful and optimistic about the future. Nearly nine in 10 (87 percent) said that having breast cancer made them a stronger person and about four in five (83 percent) said they were better able to put their lives in perspective. Due to the significant focus on early detection and recent medical and scientific advances, women are surviving breast ca... More About: Cancer , Breast Cancer , Breast , Brea , Survivors
Genomic Guides To Breast Cancer Treatment
2007-09-07 05:29:00 Three genomic tests separately predict the likelihood that a patient's breast cancer will reoccur after surgery without additional therapy, and the cancer's vulnerability to chemotherapy or hormone treatment, scientists at The University of Texas M. D. Anderson Cancer Center report at the first American Society of Clinical Oncology ASCO Breast Cancer Symposium Sept. 7-8 in San Francisco........ More About: Guides , Treatment , Cancer treatment
New link between estrogen and breast cancer
2007-08-25 15:20:00 The female sex hormone estrogen turns on a gene associated with breast cancer, as per new research by Brisbane scientists. The cancer biology team from UQ's Diamantina Institute for Cancer , Immunology and Metabolic Medicine, believe their finding will help explain the link between breast cancer and high levels of estrogen........ More About: Link , Breast Cancer , Breast , Brea
Acrylamide not linked to breast cancer
2007-08-22 02:38:00 Foods that contain acrylamide are unlikely to cause breast cancer in women, according to preliminary results of a new study involving 100,000 U.S. women. The finding, the largest epidemiological study to date exploring the possible link between acrylamide and cancer in humans, was described today at the 234th national meeting of the American Chemical Society........ More About: Cancer , Breast Cancer , Breast , Brea
Genetic Research On Ductal Carcinoma In Situ
2007-08-09 05:27:00 Today Almac Diagnostics announced a major study analysing ductal carcinoma in situ tissue samples using its novel Breast Cancer DSA microarray. DSA research tools focus on the transcriptome of an individual disease, in this case breast cancer, and contain significant additional data, relevant to the disease of interest that is not available on other generic microarrays. The study will be conducted in collaboration with Prof Adrian Harris, Cancer Research UK and Professor of Medical Oncology at the University of Oxford........
Breast cancer and hormone therapy - A looking-glass mirror?
2007-07-25 13:06:00 The medical community has been debating for a number of years whether, and to what extent, postmenopausal hormone treatment (HT) use is linked to a higher risk of breast cancer, says Professor Amos Pines, President of the International Menopause Society. Eventhough it is agreed that long-term HT slightly increases that risk, the definition of long-term use is still unclear, especially in view of data showing that it may vary significantly by type of HT (estrogen-alone vs. estrogenprogestin, brand of progestin, dosage). A new study from the Kaiser Permanente health plan[1] raises the question whether trends in breast cancer incidence and use of HT over the past 25 years may be directly linked........ More About: Cancer , Breast Cancer , Breast , Glass , Mirror
Support groups don't extend survival of metastatic breast cancer
2007-07-24 02:35:00 A new study from a team of Stanford University School of Medicine scientists led by David Spiegel, MD, shows that participating in support groups doesn't extend the lives of women with metastatic breast cancer. The results differ from oft-cited prior findings by Spiegel that showed group psychotherapy extended survival time........ More About: Cancer , Support , Breast Cancer , Breast , Survival
Fruit Intake Doesn't Reduce Chance Of Breast Cancer Recurrence
2007-07-18 06:39:00 Eating double the amount of veggies and fruits recommended by general dietary guidelines doesn't reduce the likelihood of breast cancer recurrence among women whose cancers were treated at an early stage of the disease, says a researcher at the Stanford University School of Medicine. "For breast cancer survivors who are meeting the '5-a-day' dietary goals set by the National Cancer Institute, there is no benefit to further increasing their vegetable and fiber intake in terms of preventing breast cancer recurrence," said Marcia Stefanick, PhD, professor of medicine at the Stanford Prevention Research Center and the senior author of a study that would be reported in the July 18 issue of the Journal of the American Medical Association........ More About: Fruit , Chance , Breast Cancer , Breast
Combining Trastuzumab And Chemotherapy
2007-07-10 12:52:00 A recent meta-analysis of five major breast cancer trials has confirmed that combination therapy with the antibody trastuzumab and chemotherapy improves survival in women with operable HER-2 positive breast cancer. At the ESMO Conference Lugano, Issa Dahabreh from the University of Athens reported the results of a meta-analysis of 5 trials involving more than 13,000 women whose breast cancer was amenable to surgery........ More About: Chemotherapy , Erap , Chem , Comb , Zuma
Western diet linked to increased risk of breast cancer
2007-07-10 12:52:00 Postmenopausal Asian women who eat a meat-sweet or Western diet are at greater risk of developing breast cancer than those who eat a vegetable-soy diet, as per a new study. The findings mark the first time an association between a Western diet and breast cancer has been identified in Asian women. The study, reported in the recent issue of Cancer Epidemiology, Biomarkers and Prevention, involved women in the Shanghai Breast Cancer Study. Eligible cases included all women 25 to 64 years of age who with a new diagnosis of breast cancer from August 1996 to March 1998. Controls were selected from the Shanghai Resident Registry of permanent residents in urban Shanghai........ More About: Diet , Risk
1-step breast cancer treatment
2007-06-20 18:08:00 Princess Margaret Hospital (PMH) breast cancer specialists are using a new way to treat patients by delivering a one-time dose of radiation during surgery. The procedure, called intraoperative radiation treatment, takes less than an hour and eliminates the need for further radiation therapys. On May 17, the PMH team combined the expertise of surgeons, radiation medicine specialists (radiation oncologists, physicists and therapists) and nurses to perform its first procedure. It marked the first time the portable intrabeam radiotherapy machine that makes this procedure possible has been used in Canada. The PMH team has since treated two more patients........ More About: Cancer , Treatment , Cancer treatment , Breast Cancer , Breast
Fluorescence Diffuse Optical Tomography Look At Breast Cancer
2007-06-13 20:40:00 Scientists at the University of Pennsylvania have created the first three-dimensional optical images of human breast cancer in patients based on tissue fluorescence. Fluorescence diffuse optical tomography, or FDOT, relies on the presence of fluorophore molecules in tissue that re-radiate fluorescent light after illumination by excitation light of a different color. The reconstructed images demonstrated significant tumor contrast in comparison to typical endogenous optical contrast in breast........ More About: Cancer , Optical , Breast Cancer , Breast , Opti
Plant-Based Diet For Breast Cancer Survival
2007-06-13 20:40:00 A new study in the "Journal of Clinical Oncology" reinforces current evidence showing that women with breast cancer can greatly reduce their risk of recurrence by eating a healthy plant-based diet rich in fruits and vegetables and making other healthy lifestyle choices, as per nutrition experts with The Cancer Project........ More About: Diet , Breast Cancer , Breast , Survival
Effect on Breast Tumors of DNA Alternations
2007-05-17 13:18:00 Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation. Hypermethylation is a process that causes genes that promote normal cell growth to produce proteins that cause cancerous behavior, or unregulated cell growth. Until now, data has been very limited regarding the mechanism and causes of hypermethylation, particularly for hypermethylation in breast cancer........ More About: Breast , Effect , Mors , Alter , Brea
Hair straightening chemicals does not cause breast cancer
2007-05-17 13:18:00 Chemical relaxers used to straighten hair are not associated with an increased risk of developing breast cancer among African-American women, say researchers who followed 48,167 Black Womens Health Study participants. In the recent issue of Cancer Epidemiology, Biomarkers and Prevention, researchers from Boston University and Howard University Cancer Center found no increase in breast cancer risk due to the type of hair relaxer used or the frequency and duration of use. Women who used relaxers seven or more times a year over a 20 year span or longer had the same risk as women who used the chemicals for less than a year, researchers say........ More About: Hair , Breast Cancer , Breast , Chemicals
New hereditary breast cancer gene discovered
2007-04-26 05:41:00 A new hereditary breast cancer gene has been discovered by scientists at the Lundberg Laboratory for Cancer Research and the Plastic Surgery Clinic at the Sahlgrenska Academy in Sweden. The researchers found that women with a certain hereditary deformity syndrome run a nearly twenty times higher risk of contracting breast cancer than expected........ More About: Breast Cancer , Breast , Edit , Cover
Breast Cancer: Race, Smoking And Birth Size
2007-04-16 05:09:00 Women can encounter environmental factors that increase their risk of breast cancer at various periods of their physical development, beginning before birth and extending until menopause. These non-inherited, or epigenetic, changes in DNA can correlate with risk factors for breast cancer, as per research being presented at the 2007 Annual Meeting of the American Association for Cancer Research........ More About: Race , East , Breast Cancer , Smoking
Breast cancer diagnosis from combined MRI-optics method
2007-04-14 01:15:00 By combining two techniques, magnetic resonance imaging (MRI) and near-infrared optics, scientists at Dartmouth College and Dartmouth Medical School may have devised a new, potentially more accurate method for diagnosing breast cancer. Their pilot study, demonstrating the feasibility of the concept, is reported in the April 15 issue of the journal Opti cs Letters, published by the Optical Society of America........ More About: Cancer , East , Breast Cancer , Breast
A genetic 'gang of 4' drives spread of breast cancer
2007-04-14 01:15:00 Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs. The new studies by Howard Hughes Medical Institute researchers reveal that the aberrant genes work together to promote the growth of primary breast tumors. Cooperation among the four genes also enables cancerous cells to escape into the bloodstream and penetrate through blood vessels into lung tissues........ More About: Cancer , Drive , East , Read , Breast Cancer
Computerized reminders for mammography screening
2007-03-29 12:47:00 Findings of a new Mayo Clinic study published this week in Archives of Internal Medicine show that a computerized mail and phone reminder program can significantly increase the percentage of patients receiving preventive health services and improve the value of health care. "National evidence-based guidelines say every woman over age 40 should have a yearly mammogram, but only about 65 percent of women nationally have had one in the last two years," explains Rajeev Chaudhry, M.B.B.S., the Mayo Clinic doctor who led the study. "In this study we showed we can increase that percentage through a team approach, and we're applying the findings to other chronic disease and preventive services, too"........ More About: Screen , Computer , Comp , Mind , Teri
MRI improves breast cancer diagnosis
2007-03-29 06:14:00 Women who have been diagnosed with breast cancer in one breast have a higher risk of contracting the disease in their opposite breast as well. A thorough examination of the opposite breast using mammography and ultrasound is therefore common practice. However, a number of tumours still remain undetected when using mammography. Magnetic resonance imaging (MRI) promises better results, as is shown in an inter-national study involving the University of Bonn. In almost 1,000 women with a recent diagnosis of breast cancer in one breast, MRI helped identify 30 cancers in the seemingly normal opposite breast. In women with a normal (negative) MRI of the opposite breast, there was a 99.6% confidence that in fact no breast cancer was present -- which means that if the MRI study is normal, preventive mastectomy of the opposite breast, which some women want, is definitely unnecessary. These findings have now been reported in the prestigious journal "New England Journal (NEJM)"........ More About: Cancer , East , Breast Cancer , Breast , Improve
Saliva Test for Breast Cancer
2007-03-21 04:18:00 Breast cancer is the second leading cause of death among women in the United States. In 2006, the American Cancer Society estimated that there would be 212,920 new cases of invasive breast cancer, and in that year, 40,970 women would die from it. A number of women's lives could be saved if this cancer was diagnosed earlier, and early diagnosis could be achieved if there were more and easier opportunities to do so........ More About: East , Breast Cancer , Breast , Test
Which Breast Cancer Patients Need Chemotherapy?
2007-03-14 04:53:00 Most postmenopausal women with small breast tumors don't need chemotherapy to reduce their recurrence risk after lumpectomy. To try to determine who does, a test that measures a tumor's aggressiveness based on its DNA will be tested nationally in more than 10,000 of these women. "The dilemma physicians have with these patients is, because they have such small tumors, it's hard to tell who needs chemotherapy," said Dr. Thomas A. Samuel, Medical College of Georgia hematologist/oncologist specializing in breast cancer and a study principal investigator........ More About: Chemotherapy , Cancer , Other , East , Breast Cancer
Tykerb wins FDA approval
2007-03-14 04:53:00 GlaxoSmithKline plc announced recently that the United States Food and Drug Administration (FDA) approved TYKERB (lapatinib), in combination with Xeloda (capecitabine), for the therapy of patients with advanced or metastatic breast cancer whose tumors overexpress HER2 and who have received previous treatment including an anthracycline, a taxane, and trastuzumab. It is the first targeted, once-daily oral therapy option for this patient population. TYKERB was granted Priority Review by the FDA in November 2006........ More About: Wins
African American Women And Breast Cancer?
2007-02-22 17:38:13 Why are Africa n America n women 1.5 to 2.2 times more likely than white women to die from breast cancer, despite their lower occurence rate of the disease? Is it solely because they have less access to medical care? Maybe not, as per a new analysis that will appear in an upcoming issue of the International Journal of Surgery. In a paper now available online, scientists propose that the excess mortality occurs partly because black women are more likely than white women to develop breast cancer before menopause, when surgery to remove the tumor may pose a higher risk of stimulating cancer growth........ More About: Women , Cancer , Men
Gene profiling and resistance to Herceptin
2007-02-22 17:38:13 Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast cancer. They say this advance could help further refine therapy for the 25 to 30 percent of breast cancer patients with this class of tumor........ More About: Prof , Resistance , Gene , Profil
ER and HER-2 status of breast tumors
More articles from this author:2007-02-16 05:33:03 Two critical characteristics of breast cancer that are important to therapy can be identified by measuring gene expression in the tumor, a research team led by researchers at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. Scientists developed and validated a new genomic microarray test that identifies whether a tumor's growth is fueled by the female hormone estrogen and the role of a growth factor receptor known as HER-2 that makes a tumor vulnerable to a specific drug. The status of these factors is now determined by pathology tests........ More About: East , Breast , Tumor , Tatu , Status 1, 2, 3, 4, 5 |
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