Breast cancer blogBreast cancer blogNew Article Alert From From Breast cancer blog Articles
Switch regulates breast cancer response
2008-05-09 05:06:00 A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, as per research by researchers at Emory University's Winship Cancer Institute. The results are reported in the May 9, 2008 issue of the journal Molecular Cell. Most breast cancers contain estrogen receptors, which enable them to grow in the presence of the hormone estrogen. Their presence can determine whether tumors will respond to the estrogen-blocking drug tamoxifen........ More About: Breast Cancer , Breast , Switch , Response
Mammography may be beneficial to all women
2008-04-22 03:35:00 According to researchers at The University of Texas M. D. Anderson Cancer Center, mammography, the gold-standard for breast cancer screening and early detection, has shown to significantly reduce the risk of being diagnosed with advanced stage breast cancer in women over the age of 80, an age group currently without clear guidelines recommending regular screenings........ More About: Women
MRI 'best' for looking at breast cancer and more
2008-04-17 12:01:00 The use of MRI is effective in differentiating the blood supply to medial and lateral breast tumors, which is important in therapy planning and prognosis as per a research studyconducted by scientists at the University of Miami in Miami, FL and the Rabin Medical Center in Petah Tikva, Israel. Blood supply of medial tumors is mainly through the internal mammary vessels while lateral tumors may be supplied by both the internal or lateral mammary branches........ More About: Cancer , Breast Cancer , Breast
lapatinib shrinks breast cancer tumors in6 weeks
2008-04-17 12:01:00 A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6). Dr. Angel Rodriguez, from the Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, USA, said that the work demonstrated for the first time that the tyrosine kinase inhibitor lapatinib could decrease tumour-causing breast cancer stem cells in the primary breast cancers of women receiving neoadjuvant treatment (treatment given before the primary surgery for the disease)........ More About: Breast Cancer , Weeks
Gene Variant Increases Breast Cancer Risk
2008-03-17 04:53:00 An international research consortium under the leadership of researchers of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) has shown that a common gene variant increases the risk of developing breast cancer. In roughly five to ten percent of breast cancer cases there is a family history of breast cancer- i.e., hereditary and, thus, genetic factors play a role here. Alterations in the genes known as BRCAI and BRCAII are a major cause of familial breast cancer - these are responsible for roughly 25 percent of such cases........ More About: Breast Cancer , Breast , Risk , Gene
High levels of estrogen associated with breast cancer recurrence
2008-03-07 12:34:00 Women whose breast cancer came back after therapy had almost twice as much estrogen in their blood than did women who remained cancer-free despite therapy with anti-estrogen drugs in a majority of the women as per scientists as per a research findings reported in the recent issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research........ More About: Breast Cancer , Breast , High
Test To reduce recurrence of breast cancer
2008-02-26 04:18:00 A new test that examines large sections of the sentinel lymph node for genes expressed by breast cancer could reduce the risk of recurrence and multiple surgeries, doctors say. The GeneSearch Breast Lymph Node Assay, manufactured by Veridex, L.L.C., a Johnson and Johnson company, is being used at the Medical College of Georgia to examine half of the tissue in the sentinel lymph node, the first place breast cancer typically spreads. The sample represents more than 10 times the amount of tissue examined in traditional biopsies........ More About: Cancer , Breast Cancer , Reduce , Test
Breast cancer diagnosis comes late
2008-02-01 06:01:00 Women who live in Chicago's gentrifying neighborhoods are more apt to receive a late diagnosis of breast cancer than women who live in poverty-stricken neighborhoods, University of Illinois at Chicago scientists have found. The surprising finding is as per a research findings reported in the recent issue of the Annals of Epidemiology........ More About: Cancer , Breast Cancer , Breast , Late , Diagnosis
Reducing Symptoms In Breast Cancer Patients
2008-01-29 05:40:00 Psychological interventions for cancer patients do more than just ease emotional distress - they directly improve health, new research suggests. A study of 227 patients with breast cancer observed that those who participated in a psychological intervention program were rated as having better health by a research nurse a full year after the program started........ More About: Cancer , Breast Cancer , Breast , Patients , Symptoms
NICE guidelines on breast cancer need urgent revision
2008-01-18 05:19:00 The NICE guidelines on follow-up for patients with breast cancer need urgent revision, warn experts in this weeks BMJ. More than 1.2 million women and men worldwide are diagnosed with breast cancer each year and it is now recognised as a chronic disease that can recur even after 20 -30 years. Survival continues to improve, so new cancers are now more common in a number of patients than recurrence because the therapys of the first cancer are so effective. However, follow-up protocols still vary widely both within and between countries and are not always evidence based........ More About: Cancer , Breast Cancer , Breast , Guidelines , Nice
Choosing overly aggressive treatments for breast cancer
2008-01-09 04:22:00 Despite a 1990 consensus recommendation from the National Institutes of Health (NIH) that lumpectomy plus radiation was the therapy of choice for early stage breast cancer, the United States continues to have the highest rate of mastectomy surgery among industrialized countries. Why would a person knowingly undertake a far more severe form of therapy when a lesser one would suffice? A recent survey shows that only 74 percent of women diagnosed with early stage breast cancer (ductal carcinoma in situ or DCIS) chose breast-conserving surgery even though 82 percent of their physicians had recommended the procedure........ More About: Treatments , Cancer , Breast Cancer , Breast
CT faster more accurate than mammography
2007-12-28 15:14:00 Cone-beam breast CT provides exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose to conventional 2D mammography, as per a new study by a team of scientists from the University of Texas M. D. Anderson Cancer Center in Houston. Cone-beam breast CT employs a large area x-ray beam in conjunction with a flat panel x-ray detector to scan and generate 3D images of the breast. The scanner is placed below a table on which the patient lies prone with the breast protruding through an opening. Only the breast is exposed to radiation resulting in improved image quality and sparing the rest of the patients body from unnecessary radiation exposure. The scan can be completed in less than one minute with a single complete rotation of the x-ray tube-detector gantry around the breast. Unlike conventional CT, the patient is not moved through the gantry during scanning........ More About: Aster
Taxol with avastin for metastatic breast cancer
2007-12-28 15:14:00 The positive results of the first nationwide clinical study showing the benefits of an antiangiogenic agent in breast cancer therapy are reported in the Dec. 27 issue of the New England Journal (NEJM). The study with Avastin showed the biggest improvement in metastatic breast cancer ever reported in a chemotherapy-based clinical trial. It nearly doubled the time between initiation of chemotherapy for metastatic disease and progression of the breast cancer tumors........ More About: Cancer , Breast Cancer , Breast
Scientists identify and repress breast cancer stem cells
2007-12-18 03:45:00 By manipulating highly specific gene-regulating molecules called microRNAs, researchers at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue cells that are widely thought to give rise to cancer. If certain forms of breast cancer do indeed have their origin in wayward stem cells, as we believe to be the case, then it is critical to find ways to selectively attack that tumor-initiating population, said Gregory Hannon, Ph.D., CSHL professor and Howard Hughes Medical Institute Investigator. Hannon also is head of a lab focusing on small-RNA research at CSHL and corresponding author of a paper reporting the new research, reported in the latest issue of Genes and Development........ More About: Cancer , Breast Cancer , Breast , Scientists , Stem Cells
Stem cell transplant for breast cancer
2007-12-14 04:58:00 High-dose chemotherapy and autologous stem cell transplantation, the controversial, arduous, yet once-popular combination therapy that fell out of favor as a treatment for breast cancer, has proven not to be beneficial as an adjuvant treatment for women with node-positive disease, as per an expansive analysis conducted by scientists at The University of Texas M. D. Anderson Cancer Center........ More About: Cell , Breast Cancer , Breast , Stem Cell
Accuracy of diagnostic mammograms varies by radiologist
2007-12-12 05:40:00 For women with breast symptoms such as lumps, the ability of diagnostic mammograms to detect breast cancer accurately depends strongly on which radiologist reads them, as per a Group Health study published online on December 11 in the Journal of the National Cancer Institute. When a woman gets a mammogram, she wants to know that if she has breast cancer, the mammogram will be likely to detect it, said study leader Diana Miglioretti, PhD, an associate investigator at Group Health Center for Health Studies. This is particularly important when the woman has a breast concern such as a lump........ More About: Diagnostic , MMOG , Logi , Gnostic
BRCA1 mutations cause breast cancer
2007-12-10 00:17:00 An international team of scientists led by Columbia University Medical Centers Herbert Irving Comprehensive Cancer Center and Swedens Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer. Findings show that one way BRCA1 mutations cause cancer is by knocking out a powerful tumor suppressor gene known as PTEN........ More About: Breast Cancer , Breast
Stereo Mammography Improves Cancer Detection
2007-11-29 05:02:00 A new radiological diagnostic tool called stereo mammography allows clinicians to detect more lesions and could significantly reduce the number of women who are recalled for additional tests following routine screening mammography. The findings from a clinical trial underway at Emory University were presented today at the annual meeting of the Radiological Society of North America held in Chicago........ More About: Cancer , Detection , MMOG , Prove , Stere
Extracts of catfish caught in polluted waters
2007-11-16 04:59:00 Exposing estrogen-sensitive breast cancer cells to extracts of channel catfish caught in areas with heavy sewer and industrial waste causes the cells to multiply, as per a University of Pittsburgh study being presented at the annual meeting of the American Public Health Association in Washington, D.C. The abstract, number 159141, will be presented at a special session on Contaminants in Freshwater Fish: Toxicity, Sources and Risk Communication, at 8:30 a.m., Wednesday, Nov. 7........ More About: Catfish , Caught , Waters , Extract
Simpler way to assess breast cancer risk
2007-11-16 04:59:00 A new, simpler model for predicting breast cancer risk in postmenopausal women appears to be as accurate as a more complicated method currently used to decide if women would benefit from medicine to reduce their risk of getting cancer, as per research published recently in the Journal of the National Cancer Institute........ More About: Breast Cancer , Breast , Risk
Proteins As urvival Markers in Some Breast Cancers
2007-11-16 04:59:00 New research suggests that the presence or absence of two proteins may be important markers for long-term survival in some breast-cancer patients. One of the proteins, called ErbB-4, is important for the growth and differentiation of several types of cells in the body. The second protein, called Wwox, is a tumor suppressor - it helps prevent cells from becoming malignant - and it is missing in a number of breast cancers. Researchers don't yet understand how it works........ More About: Breast , Some , Viva , Marker
Similarities In Dog, Human Breast Cancer
2007-11-16 04:59:00 Pre-cancerous mammary lesions in dogs and humans display a number of of the same characteristics, a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine. A group of researchers including Sulma Mohammed have found similarities between non-malignant lesions that are considered to carry risk for developing breast cancer in both canines and humans. Breast cancer is the second leading cause of cancer deaths in women........ More About: Cancer , Human , Breast Cancer
Extra radiation dose prevents breast cancer return
2007-10-30 05:21:00 Women 40 years and younger with early-stage breast cancer who receive an additional high dose of radiation (boost dose) after undergoing breast-conserving surgery (lumpectomy) and standard radiation therapy are almost twice as likely to be free of cancer 10 years after therapy in comparison to those who dont receive the boost dose, as per a large European study presented at the Plenary I session on October 29, 2007, at the American Society for Therapeutic Radiology and Oncologys 49th Annual Meeting in Los Angeles. Eventhough younger women benefitted most from an extra dose of radiation, the findings show that women of all ages who had a boost dose of radiation after standard therapy were more likely to be cancer-free over a 10-year period........ More About: Cancer , Breast Cancer , Breast , Return , Radiation
IMRT: Less dermatitis with breast cancer treatment
2007-10-28 21:13:00 All women treated with radiation treatment for breast cancer are at risk of developing dermatitisa sometimes-painful skin condition caused by radiation as it makes its way through the skin to the tumor area and tissue within the breast. But scientists at Fox Chase Cancer Center say women being treated with IMRT (intensity-modulated radiation treatment) are less likely to have serious dermatitis. The research was presented today at the American Society for Therapeutic Radiology and Oncologys 49th Annual Meeting in Los Angeles........ More About: Treatment , Cancer treatment , Breast Cancer , Breast
Breast cancer awareness for cardiovascular awareness
2007-10-12 06:34:00 Women who overcome breast cancer have every reason to celebrate. But a heart filled with joy may also be a heart damaged by life-saving cancer therapies, a growing body of research shows. Most breast cancer therapies today including new therapys still under development increase long-term risk of cardiovascular disease, said Lee W. Jones, Ph.D., an exercise physiologist and assistant professor in the Department of Surgery at Duke University Medical Center, Durham, NC. We dont know exactly how large the added risk is, but we believe its substantial. Recent gains in breast-cancer-specific survival could be markedly diminished by an increase in the long-term risk of cardiovascular death........ More About: Cancer , Awareness , Breast Cancer , Breast , Cardiovascular
New gene linked to breast cancer
2007-10-08 16:56:00 Scientists in a multicenter international study have identified a new gene that, if mutated, may increase a womans risk of breast cancer by more than a third. Further, the scientists observed that the gene, HMMR, interacts with the well-known breast cancer gene BRCA1. Alternations in either gene cause genetic instability and interfere with cell division, which could be a path to breast cancer developing. This leads scientists to not just a single gene, but a pathway that may be a potential target for treating or detecting breast cancer........ More About: Cancer , Breast Cancer , Breast , Gene , Brea
Dietary calcium to prevent the spread of breast cancer
2007-10-03 06:26:00 A strong skeleton is less likely to be penetrated by metastasizing cancer cells, so a fortified glass of milk might be the way to block cancers spread, as per scientists at the ANZAC Research Institute in Concord, Australia. Using a mouse model of breast cancer metastasis, the scientists observed that a calcium deficiency may increase the tendency of advanced breast cancer to target bone. Dietary calcium, they reason, might help prevent the spread of breast cancer to bone and serve as an adjuvant therapy during treatment........ More About: Cancer , Breast Cancer , Breast , Spread
New methods of beating breast cancer
2007-10-02 06:24:00 University of Manchester scientists will reveal new ways of controlling and treating breast cancer at the National Cancer Research Institute conference in Birmingham today (Monday 1 October 2007). Dr Robert Clarke and his team at the University's Cancer Studies research group have been investigating human breast cancers for the presence of stem cells - cells that generate new tumours and can cause the cancer to recur - in a series of studies funded by the charity Brea st Cancer Campaign........ More About: Methods
Breast cancer survivors optimistic
2007-09-26 05:45:00 The majority of breast cancer survivors consider themselves stronger after having the disease, as per new survey results released recently. However, the data also suggest womens knowledge about actions they can take to lessen the likelihood of recurrence is surprisingly low. The survey, which was commissioned by AstraZeneca and conducted by Harris Interactive, consisted of interviews with 543 women in the United States who had been diagnosed with breast cancer. The vast majority (92 percent) of these women reported a positive change in their lifestyles since being diagnosed with the disease and nearly two-thirds (63 percent) said they are hopeful and optimistic about the future. Nearly nine in 10 (87 percent) said that having breast cancer made them a stronger person and about four in five (83 percent) said they were better able to put their lives in perspective. Due to the significant focus on early detection and recent medical and scientific advances, women are surviving breast ca... More About: Cancer , Breast Cancer , Breast , Brea , Survivors
Genomic Guides To Breast Cancer Treatment
More articles from this author:2007-09-07 05:29:00 Three genomic tests separately predict the likelihood that a patient's breast cancer will reoccur after surgery without additional therapy, and the cancer's vulnerability to chemotherapy or hormone treatment, scientists at The University of Texas M. D. Anderson Cancer Center report at the first American Society of Clinical Oncology ASCO Breast Cancer Symposium Sept. 7-8 in San Francisco........ More About: Guides , Treatment , Cancer treatment 1, 2, 3, 4 |
|
 |
|
 |
