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Genes breast cancer risk
2009-02-17 05:21:00 Reporting this week in Nature Genetics, Wei Zheng, M.D., Ph.D, and his colleagues have identified a region on chromosome 6 that is strongly linked to breast cancer susceptibility in Asian women. This genetic "locus" may help guide efforts to find the specific genes linked with sporadic or non-inherited forms of the disease, the authors suggest........ More About: Cancer , Breast Cancer , Breast , Risk , Genes
Digital Mammograms: Is it Efficient?
2009-02-09 13:15:00 Digital mammograms take longer to interpret than film-screen mammograms, as per a research studyperformed at The University of Texas M.D. Anderson Cancer Center in Houston, Texas. The study included four radiologists who interpreted 268 digital screening mammograms and 189 film-screening mammograms. "The average interpretation time for all of our readers was 240 seconds (4 minutes) for digital screening mammograms and 127 seconds (2 minutes, 7 seconds) for film-screen screening mammograms," said Tamara Miner Haygood, MD, main author of the study. "The digital screening mammograms took nearly twice as long to interpret as the film-screen screening mammograms," said Dr. Haygood........ More About: Digital , Efficient
Those women who need radiation
2009-02-09 13:15:00 One-fifth of women who should receive radiation after a mastectomy are not getting this potentially lifesaving treatment, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. The study looked at 396 women who were treated with a mastectomy for breast cancer. The researchers found that 19 percent of women who fell clearly within guidelines recommending radiation treatment after the mastectomy did not receive that treatment........ More About: Women , Radiation
Breast cancer and ostmenopausal hormone therapy
2009-02-09 13:15:00 Women who stopped taking the postmenopausal hormone combination of estrogen plus progestin experienced a marked decline in breast cancer risk which was uncorrelation to mammography utilization change, as per a research studyfrom the Women's Health Initiative led by a Los Angeles Biomedical Research Institute (LA BioMed) investigator that was published recently in The New England Journal (NEJM)....... More About: Cancer , Breast Cancer , Breast , Therapy
Pregnancy has no impact on breast cancer
2009-02-09 13:15:00 A newly released study finds women who develop breast cancer while pregnant or soon afterwards do not experience any differences in disease severity or likelihood of survival in comparison to other women with breast cancer. The study is reported in the March 15, 2009 issue of CANCER, a peer-evaluated journal of the American Cancer Society........ More About: Pregnancy , Breast Cancer , Breast
Preventing breast cancer with broccoli
2008-12-24 05:36:00 Women should go for the broccoli when the relish tray comes around during holiday celebrations this season. While it has been known for some time that eating cruciferous vegetables, such as broccoli, cauliflower, and cabbage, can help prevent breast cancer, the mechanism by which the active substances in these vegetables inhibit cell proliferation was unknown until now........ More About: Cancer , Breast Cancer , Breast , Broccoli
New compounds show promise for eliminating breast cancer tumors
2008-11-20 03:39:00 Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up a cancer-causing protein called STAT3, and scientists have observed no negative side effects so far........ More About: Cancer , Show , Breast Cancer , Breast , Promise
Breast cancer common among women with family history
2008-11-20 03:39:00 New data presented at the American Association for Cancer Research's Seventh Annual International Frontiers in Cancer Prevention Research meeting outlines new data, which assesses breast cancer risk among women with a strong family history of breast cancer, but without a BRCA1 or BRCA2 mutation. This may facilitate earlier detection and prevention among high-risk women........ More About: Women , Family , History , Breast Cancer
Birth size is a marker of susceptibility to breast cancer
2008-10-10 06:54:00 Birth size, and in particular birth length, correlates with subsequent risk of breast cancer in adulthood, according to a new study published in PLoS Medicine by researchers at the London School of Hygiene and Tropical Medicine. Associations between birth size, perhaps as a marker of the pre-natal environment, and subsequent breast cancer risk have been identified before, but the findings from epidemiological studies have been inconsistent........ More About: Cancer , Breast Cancer , Breast , Birth , Size
Improving treatment of inherited breast cancer
2008-10-10 06:54:00 Researchers have identified some of the elusive downstream molecules that play a critical role in the development and progression of familial breast cancer. The research, published by Cell Press in the October 10th issue of the journal Molecular Cell, also identifies a compound found in grapes and red wine as an excellent candidate for therapy of some forms of breast cancer........ More About: Cancer , Treatment , Breast Cancer , Breast
Vaccine against HER2-positive breast cance
2008-09-23 06:33:00 Scientists at Wayne State University have tested a breast cancer vaccine they say completely eliminated HER2-positive tumors in mice - even cancers resistant to current anti-HER2 treatment - without any toxicity. The study, published in the September 15 issue of Cancer Research, a journal of the American Association for Cancer Research, suggests the vaccine could treat women with HER2-positive, therapy-resistant cancer or help prevent cancer recurrence. The scientists also say it might potentially be used in cancer-free women to prevent initial development of these tumors........ More About: Vaccine , Breast , Positive
3-week radiation therapy as effective as 5 weeks for breast cancer
2008-09-23 06:33:00 Boston Early-stage patients with breast cancer who receive a more intensive course of radiation to their whole breast over three weeks is as effective as the standard, less intensive five-week whole breast radiation and offers patients more convenience at a lower cost, thereby providing a better quality of life, as per a randomized, long-term study presented September 22, 2008, in the plenary session at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston........ More About: Cancer , Breast Cancer , Breast , Week , Therapy
Growth factor predicts poor outcome in breast cancer
2008-09-01 05:01:00 The response to insulin-like growth factor 1 (IGF-I) in breast cancer cells predicts an aggressive tumor that is less likely to respond to therapy, said scientists at Baylor College of Medicine in a report that appears in the current issue of the Journal of Clinical Oncology. The finding gives impetus to the movement to tailor cancer therapys to attributes of the various tumors........ More About: Cancer , Breast Cancer , Growth , Breast , Poor
New Inhibitors Of Estrogen-dependent Breast Cancer Cells
2008-07-30 08:10:00 Scientists have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. The finding, described today at a meeting of the Endocrine Society, has opened an avenue of research into new drugs to combat estrogen-dependent breast cancers. "This cell-based study is exciting because it suggests these compounds are likely to be effective in tumors that remain dependent on estrogen for growth but are resistant to current therapies," said principal investigator David J. Shapiro, a professor of biochemistry in the School of Molecular and Cellular Biology at the University of Illinois........ More About: Cancer , Breast Cancer , Breast , Dependent
2 different breast cancer screening strategies are equally effective
2008-07-30 08:10:00 An organized population-based breast cancer screening program in Norway and an approach to screening that relies on physician- and self-referrals in Vermont are equally sensitive for detecting cancer, scientists report in the July 29 online issue of the Journal of the National Cancer Institute But the recall rate for abnormal mammograms was lower in Norway........ More About: Strategies , Breast Cancer , Breast , Effective
Breast Cells Sets Stage For Abnormal Cell Division And Cancer
2008-07-30 08:10:00 A University of Michigan study reveals in detail how breast cells produce new cells that are predisposed to become malignant, unless they receive the protective action of the CHFR gene. CHFR expression is missing in more than a third of breast cancers. Analysis of this gene is also a hot area of interest among scientists trying to explain colorectal, stomach, lung and other forms of cancer........ More About: Cancer , Cell , Sets , Breast , Stage
Switch regulates breast cancer response
2008-05-09 05:06:00 A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, as per research by researchers at Emory University's Winship Cancer Institute. The results are reported in the May 9, 2008 issue of the journal Molecular Cell. Most breast cancers contain estrogen receptors, which enable them to grow in the presence of the hormone estrogen. Their presence can determine whether tumors will respond to the estrogen-blocking drug tamoxifen........ More About: Breast Cancer , Breast , Switch , Response
Mammography may be beneficial to all women
2008-04-22 03:35:00 According to researchers at The University of Texas M. D. Anderson Cancer Center, mammography, the gold-standard for breast cancer screening and early detection, has shown to significantly reduce the risk of being diagnosed with advanced stage breast cancer in women over the age of 80, an age group currently without clear guidelines recommending regular screenings........ More About: Women
lapatinib shrinks breast cancer tumors in6 weeks
2008-04-17 12:01:00 A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6). Dr. Angel Rodriguez, from the Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, USA, said that the work demonstrated for the first time that the tyrosine kinase inhibitor lapatinib could decrease tumour-causing breast cancer stem cells in the primary breast cancers of women receiving neoadjuvant treatment (treatment given before the primary surgery for the disease)........ More About: Breast Cancer , Weeks
MRI 'best' for looking at breast cancer and more
2008-04-17 12:01:00 The use of MRI is effective in differentiating the blood supply to medial and lateral breast tumors, which is important in therapy planning and prognosis as per a research studyconducted by scientists at the University of Miami in Miami, FL and the Rabin Medical Center in Petah Tikva, Israel. Blood supply of medial tumors is mainly through the internal mammary vessels while lateral tumors may be supplied by both the internal or lateral mammary branches........ More About: Cancer , Breast Cancer , Breast
Gene Variant Increases Breast Cancer Risk
2008-03-17 04:53:00 An international research consortium under the leadership of researchers of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) has shown that a common gene variant increases the risk of developing breast cancer. In roughly five to ten percent of breast cancer cases there is a family history of breast cancer- i.e., hereditary and, thus, genetic factors play a role here. Alterations in the genes known as BRCAI and BRCAII are a major cause of familial breast cancer - these are responsible for roughly 25 percent of such cases........ More About: Breast Cancer , Breast , Risk , Gene
High levels of estrogen associated with breast cancer recurrence
2008-03-07 12:34:00 Women whose breast cancer came back after therapy had almost twice as much estrogen in their blood than did women who remained cancer-free despite therapy with anti-estrogen drugs in a majority of the women as per scientists as per a research findings reported in the recent issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research........ More About: Breast Cancer , Breast , High
Test To reduce recurrence of breast cancer
2008-02-26 04:18:00 A new test that examines large sections of the sentinel lymph node for genes expressed by breast cancer could reduce the risk of recurrence and multiple surgeries, doctors say. The GeneSearch Breast Lymph Node Assay, manufactured by Veridex, L.L.C., a Johnson and Johnson company, is being used at the Medical College of Georgia to examine half of the tissue in the sentinel lymph node, the first place breast cancer typically spreads. The sample represents more than 10 times the amount of tissue examined in traditional biopsies........ More About: Cancer , Breast Cancer , Reduce , Test
Breast cancer diagnosis comes late
2008-02-01 06:01:00 Women who live in Chicago's gentrifying neighborhoods are more apt to receive a late diagnosis of breast cancer than women who live in poverty-stricken neighborhoods, University of Illinois at Chicago scientists have found. The surprising finding is as per a research findings reported in the recent issue of the Annals of Epidemiology........ More About: Cancer , Breast Cancer , Breast , Late , Diagnosis
Reducing Symptoms In Breast Cancer Patients
2008-01-29 05:40:00 Psychological interventions for cancer patients do more than just ease emotional distress - they directly improve health, new research suggests. A study of 227 patients with breast cancer observed that those who participated in a psychological intervention program were rated as having better health by a research nurse a full year after the program started........ More About: Cancer , Breast Cancer , Breast , Patients , Symptoms
NICE guidelines on breast cancer need urgent revision
2008-01-18 05:19:00 The NICE guidelines on follow-up for patients with breast cancer need urgent revision, warn experts in this weeks BMJ. More than 1.2 million women and men worldwide are diagnosed with breast cancer each year and it is now recognised as a chronic disease that can recur even after 20 -30 years. Survival continues to improve, so new cancers are now more common in a number of patients than recurrence because the therapys of the first cancer are so effective. However, follow-up protocols still vary widely both within and between countries and are not always evidence based........ More About: Cancer , Breast Cancer , Breast , Guidelines , Nice
Choosing overly aggressive treatments for breast cancer
2008-01-09 04:22:00 Despite a 1990 consensus recommendation from the National Institutes of Health (NIH) that lumpectomy plus radiation was the therapy of choice for early stage breast cancer, the United States continues to have the highest rate of mastectomy surgery among industrialized countries. Why would a person knowingly undertake a far more severe form of therapy when a lesser one would suffice? A recent survey shows that only 74 percent of women diagnosed with early stage breast cancer (ductal carcinoma in situ or DCIS) chose breast-conserving surgery even though 82 percent of their physicians had recommended the procedure........ More About: Treatments , Cancer , Breast Cancer , Breast
CT faster more accurate than mammography
2007-12-28 15:14:00 Cone-beam breast CT provides exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose to conventional 2D mammography, as per a new study by a team of scientists from the University of Texas M. D. Anderson Cancer Center in Houston. Cone-beam breast CT employs a large area x-ray beam in conjunction with a flat panel x-ray detector to scan and generate 3D images of the breast. The scanner is placed below a table on which the patient lies prone with the breast protruding through an opening. Only the breast is exposed to radiation resulting in improved image quality and sparing the rest of the patients body from unnecessary radiation exposure. The scan can be completed in less than one minute with a single complete rotation of the x-ray tube-detector gantry around the breast. Unlike conventional CT, the patient is not moved through the gantry during scanning........ More About: Aster
Taxol with avastin for metastatic breast cancer
2007-12-28 15:14:00 The positive results of the first nationwide clinical study showing the benefits of an antiangiogenic agent in breast cancer therapy are reported in the Dec. 27 issue of the New England Journal (NEJM). The study with Avastin showed the biggest improvement in metastatic breast cancer ever reported in a chemotherapy-based clinical trial. It nearly doubled the time between initiation of chemotherapy for metastatic disease and progression of the breast cancer tumors........ More About: Cancer , Breast Cancer , Breast
Scientists identify and repress breast cancer stem cells
More articles from this author:2007-12-18 03:45:00 By manipulating highly specific gene-regulating molecules called microRNAs, researchers at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue cells that are widely thought to give rise to cancer. If certain forms of breast cancer do indeed have their origin in wayward stem cells, as we believe to be the case, then it is critical to find ways to selectively attack that tumor-initiating population, said Gregory Hannon, Ph.D., CSHL professor and Howard Hughes Medical Institute Investigator. Hannon also is head of a lab focusing on small-RNA research at CSHL and corresponding author of a paper reporting the new research, reported in the latest issue of Genes and Development........ More About: Cancer , Breast Cancer , Breast , Scientists , Stem Cells 1, 2, 3, 4 |
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