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Antidepressant

Antidepressant Eases Anxiety in Older Adults
2009-01-21 09:35:00
Older adults with generalized anxiety disorder treated with the antidepressant Lexapro showed significant improvement in symptoms, a new study reports. Generalized anxiety disorder is one of the most common psychiatric disorders in older adults. Its symptoms include chronic worry and anxiety and other problems, such as muscle tension, sleep disturbance and fatigue. ?This was the first large-scale study of antidepressant medications as a treatment for anxiety disorders in older adults,? said lead researcher Dr. Eric J. Lenze, an associate professor of psychiatry at Washington University School of Medicine in St. Louis.
Hunger Hormone Ghrelin has antidepressant anti-anxiety effect
2008-06-16 12:56:00
The BBC today reported some interesting research from Nature Neuroscience which suggests an important link between Ghrelin (a hormone produced in the stomach to tell the brain to produce feelings of hunger) and depression and anxiety. It is quite hard to tell from the report whether having higher or lower doses of this hormone might help: "Our findings in mice suggest that chronic stress causes Ghrelin levels to go up, and that behaviours associated with depression and anxiety decrease when Ghrelin levels rise," This quote by Dr Zigman would seem to suggest that being hungry makes us calmer. Problem is, a lot of anxious people actually comfort eat and other certainly use foods like chocolate and ice cream to calm themselves down in a crisis. Like the antidepressant Celexa, a side effect of raised Ghrelin levels would be somewhat liable to lead to wight gain, as it induces hunger. Maybe that is something that could be remedied before any potential product came onto the...
Antidepressant Associated Changes In Semen Parameters
2008-05-27 17:31:00
Antidepressant Associated Changes In Semen ParametersUroToday.com - The authors describe 2 patients who have had severely impaired sperm concentration and motility closely associated with the use of antidepressant medications. They noted a temporal relationship between abnormal semen parameters and antidepressant therapy in these two patients. Each had normal semen parameters off medications. The evaluation of each patient was unremarkable. While on antidepressant medications, both patients produced semen samples with marked impairment of sperm concentration and/or motility. Each patient demonstrated a normalization of sperm concentration and motility after discontinuation of antidepressants. The authors hypothesize that Serotonin-reuptake inhibitor antidepressants may affect sperm transport, resulting in impaired sperm motility and concentration for some patients. http://ayur-help.blogspot.com/2-008/04/sunny-holidays-hit-sperm--count.html http://ayur-help.blogspot.com/2-008/02/coffee-...
Use Caution When Stopping Your Medication
2008-03-21 14:45:00
Suzy Cohen, R. Ph., author of The 24-Hour Pharmacist, is a licensed pharmacist with almost 20 years of clinical experience who writes a nationally syndicated column through Tribune Media Services in Chicago, appearing in the Fort Lauderdale Sun-Sentinel, the Sacramento Bee, and the Denver Post among others. A former spokesperson for the National Association of Chain Drug Stores, Suzy believes that the mind, body, and spirit are all connected. She offers a free weekly newsletter at her DearPharmacist website.Guest Blogger Suzy Cohen--QUESTION: I had a staph infection and was in the hospital. Upon release, I was prescribed an antibiotic and then another. My pharmacist warned me not to stop taking the drug, but it made me terribly sick, so I quit taking it. Tell me honestly, what happens when antibiotics are stopped early and please don’t place fear in people if we don’t want to take artificial drugs. – W.R., Silver Springs, FloridaANSWER: Your medication made you &ld...
Antidepressant effectiveness: can it be predicted within a few days of use
2008-03-13 17:02:00
In all areas of medicine, doctors want to be able to predict the effectivness of a therapy  early on in the treatment process. This is epecially true with depression and antidepressants. We have all been through the merry-go-round of antidepressant trial and error. Wouldn't it be nice to eliminate that multi-month process? Well it may be possible:Changes in the location of a single protein in the brain could be used to tell whether a person with depression is responding to an antidepressant within days of taking the drug, U.S. researchers said on Tuesday.Researchers at the University of Illinois at Chicago have discovered that a single protein in the brain changes its location within a cell membrane when an antidepressant is working, and this change could be identified with a simple blood test. Wow, wouldn't that be terrific. The entire trial and error process is a total drag. The possibility there, is if we look at blood from a patient on day zero and day four or five...
so much better than an antidepressant
2008-02-14 00:00:00
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The Antidepressant Scandal – Where Is The Outrage?
2008-02-08 00:38:00
By Bill BurnieceFebruary 07, 2008How Pharmaceutical Companies Are Suppressing Data About The Effectiveness And Safety Of Antidepressant Drugs While The FDA Looks The Other WayWe are being lied to. Our health and safety are being compromised by dangerous antidepressant drugs and the wealthy corporate giants that peddle them.Just a few weeks ago, an alarming report was released by the acclaimed New England Journal Of Medicine proving once again that the pharmaceutical industry has entirely too much influence in Washington, D.C. and specifically with the Food and Drug Administration.For the most part the antidepressant scandal has flown under the radar of most Americans. Perhaps most people missed the story with so much media attention focused on the heated presidential race.In short, the report shows the effectiveness of antidepressant drugs has been severely overhyped. It turns out the pharmaceutical companies that produce antidepressant drugs are publishing the results of only posit...
Don't Suddenly Stop Taking an Antidepressant: learn about 7 symptoms you m
2008-01-28 00:59:00
If you want to stop taking an antidepressant, it's important to speak with your doctor first, the American Academy of Family Physicians says. The doctor may recommend weaning your body off the medication gradually. People who stop an antidepressant too quickly may trigger a host of symptoms that doctors call antidepressant discontinuation syndrome. Symptoms may include: Anxiety. Feelings of depression or sadness. Moodiness and irritability. Tiredness. Headaches and dizziness. Nausea and vomiting. Diarrhea. If an antidepressant is causing an unpleasant side effect, your doctor may opt to lower your dose or prescribe a different type of antidepressant altogether. I know that the entire trial and error process is a total drag. I have been there and back. But it is critical that you strictly follow you doctor's directives.
Gene variation can effectively predict antidepressant response
2008-01-25 12:57:00
A recent study has revealed that a certain genetic variation can effectively predict the response of antidepressant drugs.   The study led by Manfred Uhr found that certain variants in the gene for a protective transporter protein that drives drugs and other substances out of the brain supports the efficacy of the antidepressants such as citalopram (trade name Celexa) and venlafaxine (Effexor).   “Antidepressants are the first-line treatment for major depression, but their overall clinical efficacy is unsatisfactory, as remission … occurs in only one-third of the patients after a trial with an adequately dosed single drug, and remission rates further decline following successive treatment failures,” wrote the researchers.     The research conducted over a mice model investigated the function of transporter protein, called P-gp that prevents entry of antidepressants into the brain.   They first knocked out genes for the transporter protein...
By: B4U India
Antidepressant Scam
2008-01-17 01:00:00
A new paper published in the New England Journal of Medicine shows that data on antidepressants was grossly manipulated. The researchers tracked all the studies, published and unpublished, on antidepressants such as prozac and paxil, to find out if outcomes affected publication..read more.....
Erythropoietin as an Antidepressant
2008-01-11 14:37:00
The recent release of the Mitchell Report concerning the use of steroids by baseball players has put the use of performance-enhancing substances by athletes in the spotlight. Erythropoietin is one such substance. Erythropoietin was a popular performance-enhancer because officials could not distinguish between natural and synthetic erythropoietin. Thousands of teams in the 1998 Tour de ...
Magnolia bark acts like antidepressant
2008-01-08 17:26:00
CM NEWS - The two active ingredients of the bark of magnolias that have generated research interests to their anti-tumour and anti-inflammatory activities also exhibits antidepressant-like effects, a new study says. Honokiol (厚朴酚) and magnolol (和厚朴酚) are the main constituents simultaneously identified in the barks of Magnolia officinalis, which have been used in traditional Chinese medicine to treat a variety of respiratory and intestinal disorders. What are the traditional applications of magnolia in TCM? Magnolias are a source of Chinese herbal materials that are widely used internationally. There are two basic materials of frequent application: the bark of magnolia, called houpu (厚朴), and the flower bud of a another magnolia, called xinyi (辛夷花) or xinyihua (辛夷花). The flower bud is used almost exclusively for treatment of sinus congestion and sinus headaches, and is taken orally or applied topically (for example, by inhaling the essential oils or plac...
Tips on Detecting Antidepressant Abuse Posted By : Kristine Gonzaga
2007-12-30 15:12:00
Antidepressant abuse is often a complicated issue since people often does not think of medicines as addictive. This article provides an overview of antidepressant abuse and insights and information on the possible effects of long-term antidepressant abuse and some tips on detecting it. More: continued here
Wellbutrin: The Right Antidepressant For You?
2007-11-30 00:00:00
Wellbutrin, also known by its scientific name Bupropion, is a very popular antidepressant. It inhibits the reuptake of both dopamine and norepinephrine. If you have never used Wellbutrin before, you need to familiarize yourself with the drug interactions and the side effects associated with it. Wellbutrin is metabolized by the liver. In lab experiments performed with ...
Antidepressant found
2007-11-22 07:27:00
A team of scientists has found that a drug used to treat depression can extend the lifespan of adult roundworms. Antidepressant drug mianserin can extend the lifespan of the nematode Caenorhabditis elegans by about 30 %. The drug may act by mimicking the effects of caloric restriction. Studies indicate that lifespan extension by mianserin involves ...
By: B-Health
NaSSAs - Noradrenergic and specific serotonergic antidepressant
2007-11-11 18:00:00
Noradrenergic and specific serotonergic antidepressant, or NaSSA's as they are known, are a modern type of anti-depressant that is being used in some cases instead of the more traditional anti depressants such as Selective Serotonin Re-uptake Inhibitors (SSRI's) and Serotonin-norepinephrine reuptake inhibitor (SNRI's).      &-#xA0;    &#-xA0;    &#x-A0;     -0;    Conquer Depression - Click Here! To the end user, the patient, there may not appear to be much difference between the three classes of drug. They are all anti-depressants, they are all taken daily over a long period of time, they have all had a bad press at some time or other and can all cause unpleasant side-effects. In fact the drugs work on different receptors, effecting the balance of different neurotransmitters in the brain. NaSSA's work on adrenergic receptors which can help to increase levels of both Serotonin a...
Antidepressant combined with painkiller is dangerous for digestive apparatu
2007-10-18 06:51:00
Use of antidepressants along with painkillers can cause bleeding in the stomach, medics has reported at the University of East England. Medicines against depression are widely used in the UK - about 1,5 million patients take it. Analgesics, like ibuprofen, are also prevalent in the country and can be ...
Antidepressant induced Liver injury
2007-07-27 06:35:00
Antidepressant-induced liver injury described in published cases were of the idiopathic type and, by definition, cannot be predicted based on dose or specific risk factors. Paroxetine had the largest number of cases within the selective serotonin-reuptake inhibitor class. Nefazodone, a serotonin-norepinephrine reuptake inhibitor, appeared to have the most serious cases and is the only antidepressant agent that carries a Food and Drug Administration Black Box Warning regarding hepatotoxicity. The tricyclic antidepressants and monoamine oxidase inhibitors are capable of producing hepatotoxicity, but fewer cases with these agents have been reported in the past 15 years, possibly due to a decline in their use. Causality has not been well established in all reports due to the concurrent use of other drugs and/or underlying liver disease.Most antidepressant agents have the potential to produce idiopathic liver injury. There is no way to prevent idiopathic DILI, but the severity of the rea...
Boom time for antidepressants!
2007-07-12 00:00:00
More often prescribed than drugs to treat high blood pressure, high cholesterol, asthma, or headaches? With latest figures showing that antidepressants have become the most commonly prescribed drugs in the United States, has depression become more prevailent or are doctors medicating unhappiness? Common symptions of depression include: Persistent sad, anxious, or “empty” mood ...
The most prescribed drugs in the United States are antidepressants accordin
2007-07-11 12:35:00
According to a government study, antidepressants have become the most commonly prescribed drugs in the United States. They're prescribed more than drugs to treat high blood pressure, high cholesterol, asthma, or headaches. In its study, the U.S. Centers for Disease Control and Prevention looked at 2.4 billion drugs prescribed in visits to doctors and hospitals in 2005. Of those, 118 million were for antidepressants. High blood pressure drugs were the next most-common with 113 million prescriptionsThe use of antidepressants and other psychotropic drugs -- those that affect brain chemistry -- has skyrocketed over the last decade. Adult use of antidepressants almost tripled between the periods 1988-1994 and 1999-2000. Between 1995 and 2002, the most recent year for which statistics are available, the use of these drugs rose 48 percent, the CDC reported. Of 2.4 billion prescriptions in 2005, 118 million were for antidepressants. Many psychiatrists see this statistic sign that final...
Mothers? Antidepressants May Lead to Abnormalities in Newborn
2007-07-10 08:30:00
A newborn?s risk of exhibiting drug withdrawal symptoms and respiratory abnormalities appears to increase with prenatal exposure to certain antidepressants, according to two new studies. Before prescribing this type of medication to pregnant women, the doctors are urged by researchers to carefully consider these findings. The risk of a respiratory disorder in ...
Selection of Antidepressants: Wellbutrin — bupropion [The Corpus Call
2007-07-03 15:41:00
This is another post in a series detailing the selection of antidepressant medication.  Use the “Antidepressants” link in the “Categories” part of the sidebar to find the other posts in the series. In this post, I am sort of assuming that the reader has read the previous posts, or has an adequate fund of general knowledge on the subject. Bupropion is not a member of a family.  Most antidepressants can be placed in a family of drugs that share similar properties, but there is no other drug like it, as of the time of this writing.  It is sometimes referred to as a norepinephrine-dopamine reuptake inhibitor (NDRI) but in my mind it does not make sense to give it a class name if there is only one member of the class. (It is rumored that an active metabolite, hydroxybupropion, may be marketed eventually, but development is on hold at the present time.) Bupropion, then, is unique.  For that reason, it deserves particular attention… Read ...
Antidepressants, a Canary in the Coal Mine
2007-06-29 00:39:00
Antidepressants, one of my favorite topics, are once again in the news. I"ve already explored the connection between antidepressants and a number of personality disorders, but the new studies take us in an entirely different direction and only add fuel to the fire.Two studies released today indicate that Infants born to women taking prescription antidepressants during the first trimester of their pregnancies have an increased risk of serious birth defects. At first glance, the results seem chilling. For example:
Antidepressants and birth defects: new New England Journal of Medicine stud
2007-06-28 22:04:00
I receive quite a few e-mails from women who are concerned about taking antidepressants while pregnant. Many of these women who suffer from depression worry about having to discontinue antidepressants while pregnant and fear postpartum depression. About 10 percent of pregnant women suffer from depression, according to the March of Dimes. The CDC says every pregnancy has a 3 percent risk of a major birth defect, regardless of exposures. I wanted to share the results of a  new study published today in The New England Journal of Medicine. The study concluded:Newer antidepressant drugs may increase the risk of birth defects but the risk remains very remote. The drugs, known as selective serotonin reuptake inhibitors or SSRIs, may cause a very small increase in the number of heart defects, but even this is unclear.According to the U.S. Centers for Disease Control and Prevention(CDC), "researchers, did, however, find associations between SSRI use and three specific birth defect...
It's in your genes: new antidepressant medications may soon be able to pred
2007-06-19 17:22:00
I know that a course of antidepressant treatments is essentially a "hit or miss" process. It can take several months for a new antidepressant medication to work, if it is going to work. Then if it is not effective, your psychiatrist will prescribe another new antidepressant medication and you have to wait another two months to determine if the new antidepressant is effective for you. Or if you can tolerate the antidepressant's side effects. Common antidepressant side effects can include unwanted weight gain, nausea, anorgasma ( a common side effect with Lexapro), sexual dysfunction, etc.Good news is on the horizon for this "hit or miss" process. It will soon be possible for a psychiatrist to biologically personalize treatments. With a simple blood test, the doctor will be able to characterize a patient’s unique genetic profile, determining what biological type of depression the patient has and which antidepressant is likely to work best. Scientists have identi...
Women Who Stop Antidepressant Suffer A Relapse
2007-06-06 08:34:00
Is it safe to take antidepressants during pregnancy? It?s hard to find a straight answer on whether expectant women should continue taking antidepressants during pregnancy and what effect the medication has on newborns. Recent studies have been as contradictory and unclear as news about the benefits or drawbacks to a ...
Antidepressants to Carry New Warning
2007-05-16 09:23:00
An antidepressant, in the most common usage, is a psychiatric medication taken to alleviate clinical depression or dysthymia (’milder’ depression). Several groups of drugs are particularly associated with the term, notably MAOIs and tricyclics (whose serendipitous discovery and psychiatric use dates from the 1950s) as well as SSRIs and more recent ...
Antidepressants: Good and Bad
2007-05-14 21:22:00
As expected, a number of people wrote in to comment on the newsletter I wrote recently on antidepressants. Unlike the last time, however, most of the comments were supportive. In particular, I received a number from readers in Europe who told me that what I advocated (using antidepressants as the final option, not the first) was already the rule of thumb on the Continent.
Antidepressants Linked to Increased Bone Fracture Risk
2007-05-12 09:07:00
An antidepressant, in the most common usage, is a psychiatric medication taken to alleviate clinical depression or dysthymia (’milder’ depression). Several groups of drugs are particularly associated with the term, notably MAOIs and tricyclics (whose serendipitous discovery and psychiatric use dates from the 1950s) as well as SSRIs and more recent ...
Antidepressants not dangerous for children, claims research
2007-05-09 09:37:00
Whenever there is a dilemma about a fact, we, the medical science people conduct a research, and that helps in a way to understand the trends and the curves that a particular dilemma can take. Recently there has been a volunteered debate on the effects of the so called antidepressants on the children. There ...
Antidepressants linked to suicide risk in young adults
2007-05-06 12:56:00
May 2nd - Food and Drug Administration , otherwise known as FDA proposed that the antidepressant manufacturers shall include a warning of increased risk of suicidal thinking and behavior in young adults aged 18 to 24 during initial treatment on the existing black box of their products labeling. FDA proposal is based on their internal committee's finding on 77,000 adult patients with major depressive disorders.
Risks and Antidepressants
2007-05-04 06:00:00
The FDA has just announced that it is seeking an update to the warning labels required on antidepressants, advising consumers that the drug may increase the risk of suicide slightly for those under the age 25.  It’s a difficult situation, as the increase in suicidal thoughts and behavior is considered strong enough to require warning, but is still a very small risk in terms of overall population: It's a "quite small" risk, says Thomas Laughren, MD, director of the FDA's Division of Psychiatry Products. "If you look at 1,000 patients treated, for those under 18 we expect to see 14 cases with increased suicidal thinking and behavior linked to taking these drugs," Laughren said in a news conference. "In young adults aged 18 to 24, you'd see five additional cases of suicidality out of 1,000 people." There is no evidence that the drugs raise suicide risk in people over age 25, the FDA says. Instead, Laughren says antidepressants appear to decrease suicidality in older adult...
Bristol Acupuncture Clinic Replaces Antidepressants With Acupuncture
2007-04-18 03:00:00
Acupuncture is an ancient practice which has helped to ease many human ailments from internal digestion problems to the easing of aches and pains. It has also helped many people with various psychological problems and addictions. The treatment of anxiety and depression is an area in which The Oriental Medicine Practice’s Bristol Acupuncture Clinic have ...
No antidepressant benefit for bipolar patients
2007-03-29 03:20:00
Antidepressants, which are widely prescribed with mood stabilizers to treat patients with bipolar disorder, do not work in relieving depressive symptoms, a large federal study reported today.
By: Get rich
Antidepressants and Suicide
2007-01-20 19:03:00
Anyone taking or contemplating anti-depressants for treatment of depression have been concerned about the blackbox warnings from the FDA. The FDA has issued blanket warnings to anyone considering or taking anti-depressants that they may actually induce suicidal thinking. The truth is that there is still very little and conflicting information about the risks. Highlighting the risks in the way the FDA did by issuing a blackbox warning has been controversial. The problem is that the risks have been assessed in only a few studies and it is not clear what is happening. The other problem is that anti-depressants also treat and prevent suicidal behavior. Not taking an anti-depressant when you need one can also be a grave risk. There is concern within the psychiatric and advocate community that the FDA is driven more by politics than science these days. A coalition of psychiatry and advocate organizations has issued an open letter to the FDA pointing to the life and death consequences o...
Antidepressants on top of mood stabilizers not helpful in most people with
1970-01-01 00:59:00
Giving patients with bipolar disorder antidepressants on top of their mood stabilizer medications does not relieve their depression any better than an inactive pill called a placebo, said researchers who reported on this large, multi-center study that appears online today in the New England Journal of Medicine. ?If you are on mood stabilizer treatment, which is the best first-line treatment for most people with bipolar disorder, adding an antidepressant usually does not help you out of your depression,? said Dr. Lauren Marangell, the Brown Foundation Chair of the Psychopharmacology of Mood Disorders in the Menninger Department of Psychiatry at Baylor College of Medicine and one of the lead investigators in the study. ?As first line treatment for depression in bipolar disorder, we do not recommend antidepressants.?
Psychotherapy and antidepressant medication
1970-01-01 00:59:00
Psychotherapy and antidepressant medication: Scope, procedure and interaction: A survey of psychotherapists? experience In two opinion surveys, a total of 130 psychotherapists and psychotherapy students were asked to respond to questions about different aspects of treatment with psychotherapy combined with antidepressant medication. Their answers show that, at psychotherapy units belonging to regional psychiatry, an average of half the patients and at non-regional psychotherapy units nearly a quarter of the patient group were prescribed antidepressant medication.
A Fast Acting Antidepressant
1970-01-01 00:59:00
A glaring shortfall of current antidepressant medications involves the need to take a drug for a particular length of time (often a month or more) before the effectiveness of the medication can be ascertained. During the long wait to begin feeling the effects of conventional medications, individuals may worsen, raising the risk of suicide for some. Depressive disorders also affect children and adolescents.
Indications for Antidepressant use in patients with chronic pain disorders
1970-01-01 00:59:00
Chronic pain is common; an estimated 20% of primary care visits focus on this problem. Nearly 25% of patients with diabetes develop neuropathic pain. Traumas, strokes, HIV/AIDS, and alcohol abuse are other common medical problems that can produce a chronic pain disorder. The aging American population guarantees the continued prominence of chronic pain disorders. Managing chronic pain is one of the most challenging problems that both physicians and patients face. Extensive diagnostic assessment may shed little light on the etiology of the disorder, leaving both the physician and the patient in an uncomfortable position. The physician?s goal is pain control, which may not produce total relief from symptoms. Multiple interventions may be required to manage the patient?s expectations when intractable pain relentlessly intrudes on his or her daily life. An empathetic health care provider can offer education, emotional support, medical referrals as needed, and, perhaps most importantly...
Recognising and managing antidepressant discontinuation symptoms
1970-01-01 00:59:00
Antidepressant discontinuation symptoms occur with all classes of antidepressant. A well-described discontinuation syndrome occurs with the selective serotonin reuptake inhibitors, common symptoms including dizziness, headache, nausea and lethargy. Rare antidepressant discontinuation syndromes include extrapyramidal syndromes and mania/hypomania. All these syndromes, even isolated discontinuation symptoms, share three common features that facilitate diagnosis; abrupt onset within days of stopping the antidepressant, a short duration when untreated and rapid resolution when the antidepressant is reinstated.
Antidepressant success may vary by race
1970-01-01 00:59:00
Black and Hispanic adults with depression may not do as well on drug therapy as whites do, a study suggests. Researchers found that among nearly 2,700 U.S. adults receiving an antidepressant for major depression, African Americans and Latinos had lower success rates than their white counterparts. 
Suicides increased after antidepressant warning: Manitoba researcher
1970-01-01 00:59:00
Youth suicides increased after Health Canada warned about the use of antidepressants, a University of Manitoba researcher has found. Health Canada issued a notice in 2004 that antidepressant drugs were linked to increased rates of suicidal thoughts in children and teens. It advised patients under the age of 18 who were being treated with selective serotonin reuptake inhibitors (SSRIs) or serotonin noradrenalin reuptake inhibitors (SNRIs) to consult their physicians. A similar warning was issued around the same time in the U.S.
Is Your Antidepressant And Reflux Disease Linked
0000-00-00 00:00:00
There could be a link between antidepressant and reflux disease Therefore if you take antidepressants and are suffering from frequent acid reflux/GERD gastroesophageal reflux disease your antidepressant medication could be contributing to the symptoms you are experiencing
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