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Cervical cancer vaccines cannot treat women who are already infected
2007-08-19 04:41:00 A new study suggests that cervical cancer vaccines for human papillomavirus (HPV) do not reduce or eliminate preexisting infections. Study researcher Allan Hildesheim at the National Cancer Institute says that, based on this research, the best approach is to vaccinate girls and women before they initiate any sexual activity. The CDC recommends that girls should be vaccinated ...
By: Cancer war
[immunology] vaccination with ny-eso-1 protein and cpg in montanide induces
2007-05-24 01:05:00 The use of recombinant tumor antigen proteins is a realistic approach for the development of generic cancer vaccines, but the… (Source: Proceedings of the National Academy of Sciences) More: continued here
Clinical trial of autologous formalin-fixed tumor vaccine for glioblastoma
2007-05-24 01:05:00 Cancer Science Volume 0, Issue 0, Page ???-???. (Source: Cancer Science) More: continued here
Hpv vaccine protects against vulvar and vaginal cancers
2007-05-23 04:05:00 Data show that the human papillomavirus quadrivalent vaccine can protect against vulval and vaginal cancers in addition to offering protection against cervical cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines) More: continued here
Foundation will give biggest grant ever
2007-05-23 03:05:00 The Health Care Foundation of Greater Kansas City is scheduled to announce its largest single grant — $2 million — to provide a new vaccine against the virus that causes cervical cancer. (Source: bizjournals.com Health Care:Pharmaceuticals headlines) More: continued here
Pancreatic cancer ? outlook: gene therapy
2007-05-08 08:05:00 Abstract Gene therapy offers an elegant alternative to toxic chemotherapy regimens, mostly without severe side effects. Cancer gene therapy was among the first applications. Following the enthusiasm in the early nineties, a more rationale view is the recent way to look at it. This tutorial review looks upon the tools of gene therapy and the principle ...
Spleen-selective gene transfer following the administration of naked plasmi
2007-05-04 14:05:00 Related Articles Spleen-Selective Gene Transfer Following the Administration of Naked Plasmid DNA onto the Spleen Surface in Mice. Biol Pharm Bull. 2007 May;30(5):941-5 Authors: Nakamura J, Fumoto S, Kawanami R, Kodama Y, Nishi J, Nakashima M, Sasaki H, Nishida K The purpose of present study was to examine spleen-selective gene transfer following the administration of naked plasmid DNA ...
Some doctors refuse to purchase cervical cancer vaccine because of low reim
2007-05-02 20:05:00 Some physicians are refusing to purchase Merck’s cervical cancer vaccine Gardasil or are restricting who receives it because they say insurance reimbursements for the vaccine are too low, the Washington Post reports. The issue “highlights a long-simmering dispute over reimbursement for immunization” that has “accelerated as the number of costly new vaccines has proliferated,”… (Source: ...
Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccin
2007-04-27 15:04:00 Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccines Nature 446, 1000 (2007). doi:10.1038/nature05813 Authors: Danica P. Galonić & David Y. Gin Therapeutic vaccines derived from carbohydrate antigen–adjuvant combinations are a promising approach for cancer immunotherapy. One of the critical limitations in this area is access to sufficient quantities of tumour-associated carbohydrate antigens and glycoconjugate adjuvants. At present, availability ...
Actions taken on hpv vaccine legislation in colorado, south carolina, washi
2007-04-27 01:04:00 The following highlights recent state news related to human papillomavirus vaccines. Merck’s HPV vaccine Gardasil and GlaxoSmithKline’s HPV vaccine Cervarix in clinical trials have been shown to be 100% effective in preventing infection with HPV strains 16 and 18, which together cause about 70% of cervical cancer cases. [click link for full article] (Source: Health ...
Texas showdown on hpv vaccine order
(ap)
2007-04-27 00:04:00 AP - Texas lawmakers rejected Gov. Rick Perry’s anti-cancer vaccine order Wednesday, sending him a bill that blocks state officials from requiring the shots for at least four years. (Source: Yahoo! News: Health News) More: continued here
Showdown in texas over hpv vaccine order
2007-04-27 00:04:00 Texas lawmakers rejected Gov. Rick Perry’s anti-cancer vaccine order Wednesday, sending him a bill that blocks state officials … (Source: USATODAY.com Health) More: continued here
Identification of hla-drb1*1501-restricted t-cell epitopes from human prost
2007-04-27 00:04:00 The crucial role of CD4 T-cells in anti-tumor immune response is widely recognized, yet the identification of HLA class II-restricted epitopes derived from tumor antigens has lagged behind compared to class I epitopes. This is particularly true for prostate cancer. Based on the hypothesis that successful cancer immunotherapy will likely resemble autoimmunity, we searched for ...
When is gardasil vaccine likely to be included in nhs immunisation programm
2007-04-24 15:04:00 Unfortunately, we have been unable to locate any specific information on a likely timetable. A search of the Department of Health website found only a single document on the subject (Source: NLH Question Answering Service) More: continued here
Public ?clamoring? for free cervical cancer vaccine in nh
2007-04-24 15:04:00 Read full story for latest details. (Source: CNN.com - Health) More: continued here
Shared mhc class ii-dependent melanoma ribosomal protein l8 identified by p
2007-04-24 15:04:00 Antigens recognized by T helper (Th) cells in the context of MHC class II molecules have vaccine potential against cancer and infectious agents. We have described previously a melanoma patient’s HLA-DR7–restricted Th cell clone recognizing an antigen, which is shared among melanoma and glioma cells derived from various patients. Here, this antigen was cloned using ...
Hpv vaccines: the beginning of the end for cervical cancer.
2007-04-23 15:04:00 Related Articles HPV vaccines: the beginning of the end for cervical cancer. Curr Opin Immunol. 2007 Apr;19(2):232-8 Authors: Leggatt GR, Frazer IH Vaccines prophylactic against infection with human papillomavirus (HPV) are based on alum adjuvanted virus-like particles. Two such vaccines have recently been shown to prevent persistent HPV infection and associated cervical cancer precursor lesions. The genotype-specific neutralising ...
Aging and the dendritic cell system: implications for cancer.
2007-04-23 15:04:00 Related Articles Aging and the dendritic cell system: Implications for cancer. Crit Rev Oncol Hematol. 2007 Apr 17; Authors: Shurin MR, Shurin GV, Chatta GS The immune system shows a decline in responsiveness to antigens both with aging, as well as in the presence of tumors. The malfunction of the immune system with age can be attributed to ...
Regulatory t cells and cancer.
2007-04-23 12:04:00 Related Articles Regulatory T cells and cancer. Curr Opin Immunol. 2007 Apr;19(2):217-23 Authors: Wang HY, Wang RF Increasing evidence indicates that T regulatory (Treg) cells have the potent ability to suppress host immune responses, thus preventing autoimmune diseases. However, recent studies demonstrate that tumor cells can recruit these Treg cells to inhibit antitumor immunity in the tumor microenvironment, ...
Immunogenicity of the carcinoembryonic antigen derived peptide 694 in hla-a
2007-04-22 19:04:00 Abstract Carcinoembr-yonic antigen (CEACAM5) is commonly overexpressed in human colon cancer. Several antigenic peptides recognized by cytolytic CD8+ T-cells have been identified and used in colon cancer phase-I vaccination clinical trials. The HLA-A*0201-binding CEA694?702 peptide was recently isolated from acid eluted MHC-I associated peptides from a human colon tumor cell line. However, the immunogenicity of this ...
Single administration of low dose cyclophosphamide augments the antitumor e
2007-04-21 09:04:00 Abstract Single administration of low dose cyclophosphamide (CTX) was previously reported to enhance the antitumor efficacy of immunotherapies. To investigate the possible mechanisms for this effect, we examined whether a single administration of low dose CTX could augment the immunogenicity of dendritic cell (DC) vaccines. Fifty milligrams per kilogram body weight dose of CTX was administrated ...
In situ detection of antigen-specific t cells in cryo-sections using mhc cl
2007-04-21 08:04:00 Abstract Application- of tetrameric MHC class I-peptide complexes has significantly improved the monitoring of antigen-specific T cell immune responses in mouse models as well as in clinical studies. Especially MHC class I tetramer analysis of tumor-specific T cells in suspension or on thick vibratome sections from viable tissue has been proven extremely useful. Using the well-characterized ... |
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