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MMR Vaccine Information - Measles, Mumps and Rubella
2008-03-22 10:25:00 Why should it be done? Measles, mumps and rubella are diseases with serious complications: Measles causes a range of symptoms from ear infection and bronchitis to convulsions (fits) or brain damage, and can be fatal. Mumps used to be the main cause of viral meningitis in children. Also causes temporary deafness, miscarriage, inflammation of the pancreas, and Pain ...
Increased hif1[alpha] in sdh and fh deficient tumors does not cause microsa
2007-05-24 03:05:00 Germline mutations in nuclear genes encoding mitochondrial enzymes fumarate hydratase (FH) and succinate dehydrogenase (subunits SDHB/C/D) have been implicated in the development of tumor syndromes referred to as hereditary leiomyomatosis and renal cell cancer (HLRCC) and hereditary paragangliomatosis (HPGL), respectively. FH and SDH are operating in the tricarboxylic acid cycle (the TCA cycle, the Krebs ...
Functional analysis of human mlh1 variants using yeast and in vitro mismatc
2007-05-18 23:05:00 The functional characterization of nonsynonymous single nucleotide polymorphisms in human mismatch repair (MMR) genes has been critical to evaluate their pathogenicity for hereditary nonpolyposis colorectal cancer. We previously established an assay for detecting loss-of-function mutations in the MLH1 gene using a dominant mutator effect of human MLH1 expressed in Saccharomyces cerevisiae. The purpose of this ...
Congenital rubella syndrome in a child born to liberian refugees: clinical
2007-05-08 08:05:00 We describe a case of congenital rubella syndrome with typical stigmata in an infant born in New Hampshire to Liberian refugees. The infant’s clinical specimens were tested for rubella. Rubella immunity status was sought for contacts. The infant’s specimen cultures grew wild-type rubella virus; serum immunoglobulin M and G were positive. Eighteen of 20 contacts ...
Loss of apaf-1 expression is associated with tumour progression and adverse
2007-05-06 07:05:00 Related Articles Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer. Eur J Cancer. 2007 Apr;43(6):1101-7 Authors: Zlobec I, Minoo P, Baker K, Haegert D, Khetani K, Tornillo L, Terracciano L, Jass JR, Lugli A The aim of this study was to determine the prognostic value of APAF-1 in colorectal cancer (CRC). ...
Nuclear localization of human dna mismatch repair protein exonuclease 1 (he
2007-05-04 17:05:00 Human exonuclease 1 (hEXO1) is implicated in DNA mismatch repair (MMR) and mutations in hEXO1 may be associated with hereditary nonpolyposis colorectal cancer (HNPCC). Since the subcellular localization of MMR proteins is essential for proper MMR function, we characterized possible nuclear localization signals (NLSs) in hEXO1. Using fluorescent fusion proteins, we show that the sequence ...
Measles, mumps, and rubella: prevention
2007-02-07 12:41:01 New evidence; previous conclusions confirmed for Monovalent measles vaccine or combined MMR vaccine versus placebo or no vaccine and Monovalent mumps vaccine or combined MMR vaccine versus placebo or no vaccine. (Source: Clinical Evidence) More: continued here
Measles, rubella, mumps, and varicella seroprevalence among health care wor
2007-02-03 06:30:02 Related Articles Measles, rubella, mumps, and varicella seroprevalence among health care workers in Turkey: is prevaccination screening cost-effective? Am J Infect Control. 2006 Nov;34(9):583-7 Authors: Celikbas A, Ergonul O, Aksaray S, Tuygun N, Esener H, Tanir G, Eren S, Baykam N, Guvener E, Dokuzoguz B BACKGROUND: To investigate the immune status of health care workers (HCWs) against measles, rubella, mumps, and varicella zoster (MMRV) in Turkey and to define an appropriate vaccination program among HCWs. METHODS: Voluntary HCWs from a children’s hospital and a general hospital were included in the study between March and May 2005. The specific IgG antibodies against MMRV viruses were screened by ELISA. RESULTS: Three hundred sixty-three HCWs participated in the study; 186 (51%) were physicians, 118 (33%) were nurses, 36 (10%) were housekeeping staff, and 23 (6%) were medical technicians. The proportion of HCWs who had antibodies against measles was 98.6%; rubella, 98.3%...
Evaluation of immunity against rubella in iranian after mass campaign for m
2007-02-03 06:30:02 Related Articles Evaluation of immunity against rubella in Iranian after mass campaign for measles-rubella vaccination on December 2003. Am J Infect Control. 2006 Nov;34(9):588-92 Authors: Hamkar R, Jalilvand S, Mokhtari-Azad T, Jelyani KN, Nategh R BACKGROUND: Prevention of congenital rubella syndrome (CRS) is the main goal of rubella immunization. The World Health Organization (WHO) recommends that countries undertaking measles elimination should take the opportunity to eliminate rubella as well through use of measles-rubella (MR) or measles-mumps-rubella (MMR) vaccine in their childhood immunization programs and campaigns. On December 2003, during a mass campaign for measles-rubella vaccination in Iran, more than 33 million doses of vaccine were administered to 5- to 25-year-old males and females. METHODS: In this study, immunoglobulin (Ig)G avidity assay was used to evaluate the rubella vaccine produced immunity among susceptible populations. RESULTS: Findings indicated that ...
Immunogenicity and safety of a second dose of measles-mumps-rubella-varicel
2007-01-27 06:14:01 (Source: The Pediatric Infectious Disease Journal - Current Table Of Contents) More: continued here |
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